Cannabinoid Hyperemesis Syndrome Masquerading as Uremia: An Educational Case Report

Canadian Journal of Kidney Health and Disease
Judith Klassen, Gail Wilson

Abstract

With marijuana legalization, clinicians need to be aware of Cannabinoid Hyperemesis Syndrome (CHS), which may masquerade as other disease states such as uremia. A 37-year-old man with bipolar affective disease treated with lithium had progressive renal insufficiency presumably on the basis of interstitial fibrosis. He developed persistent and severe nausea and vomiting which was assumed to be on the basis of uremia. Predating the nausea and vomiting was a history of daily marijuana use. Renal insufficiency, bipolar affective disease, and intractable nausea and vomiting. Dialysis was initiated but did not improve his symptoms and multiple investigations revealed no other cause. Abstinence from marijuana use resulted in complete resolution of symptoms. The patient elected to discontinue dialysis and was still alive 7 months later. We concluded the nausea and vomiting were not on a uremic basis but more likely due to CHS. With more widespread use of marijuana, it is important to be aware of CHS, which may be confused with uremia in patients with concomitant renal insufficiency.

References

Jun 29, 2010·The New England Journal of Medicine·Bruce A CooperUNKNOWN IDEAL Study
Feb 7, 2012·Mayo Clinic Proceedings·Douglas A SimonettoJason H Szostek
Jan 15, 2014·The American Journal of Emergency Medicine·Joseph Habboushe, Jennifer Sedor
Mar 14, 2014·Seminars in Dialysis·Matthew B Rivara, Rajnish Mehrotra
Dec 22, 2016·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·Cecilia J SorensenAndrew A Monte

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Citations

Jan 24, 2020·Current Opinion in Nephrology and Hypertension·Joshua L Rein

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