Cannabis abuse and severity of psychotic and affective disorders in Israeli psychiatric inpatients

Comprehensive Psychiatry
Gregory KatzLeon Grunhaus

Abstract

The influence of cannabis abuse on the severity of existing psychotic and affective symptoms is still unclear. Among 470 consecutively admitted psychotic or affective patients, 54 active (in the previous month) cannabis abusers were detected via urine tests (Sure Step TM kits; Applied Biotech Inc, San Diego, Calif) and Structured Clinical Interview for DSM-IV (SCID- IV) questionnaire. In 24 cases, substances other than cannabis were abused; 392 patients were nonabusers. All patients were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria. The following rating scales were used: Hamilton Depression Rating Scale (HAM-D-21), Positive and Negative Syndrome Scale (PANSS), and Young Mania Rating Scale (YMRS). Cannabis abusers (n = 54) were significantly younger and more frequently males than nonuser patients. In this group, there were more schizophrenic patients and fewer affective and anxiety patients (chi(2) = 11.76; P < .01). The double-diagnosed patients had more prominent psychotic symptoms than the nonusers (n = 392)-PANSS positive: 19.056 +/- 8.30 vs 16.128 +/- 8.031 (P < .02; t(446) = 2.510). The difference was statistically significant for hallucinatory behavior, excitem...Continue Reading

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Citations

Mar 28, 2012·Current Opinion in Psychiatry·Jagadisha ThirthalliGautham Arunachal
Jun 23, 2015·Neural Plasticity·Rafaela Torres Portugal LeiteFábio Gomes de Matos E Souza
Dec 18, 2014·Asian Journal of Psychiatry·Nopporn Tantirangsee, Sawitri Assanangkornchai
Jan 23, 2018·The Cochrane Database of Systematic Reviews·Henk S TemminghDan J Stein
Jun 22, 2020·Journal of Psychiatric Research·S MaderoM Balcells

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