Abstract
The influence of cannabis abuse on the severity of existing psychotic and affective symptoms is still unclear. Among 470 consecutively admitted psychotic or affective patients, 54 active (in the previous month) cannabis abusers were detected via urine tests (Sure Step TM kits; Applied Biotech Inc, San Diego, Calif) and Structured Clinical Interview for DSM-IV (SCID- IV) questionnaire. In 24 cases, substances other than cannabis were abused; 392 patients were nonabusers. All patients were diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, criteria. The following rating scales were used: Hamilton Depression Rating Scale (HAM-D-21), Positive and Negative Syndrome Scale (PANSS), and Young Mania Rating Scale (YMRS). Cannabis abusers (n = 54) were significantly younger and more frequently males than nonuser patients. In this group, there were more schizophrenic patients and fewer affective and anxiety patients (chi(2) = 11.76; P < .01). The double-diagnosed patients had more prominent psychotic symptoms than the nonusers (n = 392)-PANSS positive: 19.056 +/- 8.30 vs 16.128 +/- 8.031 (P < .02; t(446) = 2.510). The difference was statistically significant for hallucinatory behavior, excitem...Continue Reading
References
Jan 1, 1976·Annals of the New York Academy of Sciences·F Knight
Aug 1, 1990·The Journal of Nervous and Mental Disease·A Y Tien, J C Anthony
Feb 1, 1974·The American Journal of Psychiatry·E J KhantzianA F Schatzberg
Aug 6, 1998·Journal of Psychoactive Drugs·L Grinspoon, J B Bakalar
Feb 16, 1999·Schizophrenia Research·G Scheller-GilkeyF W Brown
Mar 7, 2001·The American Journal of Psychiatry·A DervauxM O Krebs
Aug 16, 2002·American Journal of Epidemiology·J van OsH Verdoux
Oct 5, 2002·The Journal of Clinical Psychiatry·Joseph F Goldberg, Joyce E Whiteside
Nov 7, 2002·Archives of General Psychiatry·David W BrookMartin Whiteman
Feb 5, 2005·Biological Psychiatry·E Fuller TorreyMichael B Knable
Mar 23, 2005·Biological Psychiatry·Deepak Cyril D'SouzaJohn Harrison Krystal
Jan 28, 2006·Psychological Medicine·E J RegeerJ van Os
Jun 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Nicola J WilesGlyn Lewis
Jun 24, 2006·Journal of Affective Disorders·Cécile HenquetJim van Os
Jun 30, 2006·Schizophrenia Research·Caroline DubertretPhilip Gorwood
Feb 3, 2007·The American Journal of Psychiatry·Fernando S GoesJames B Potash
Feb 10, 2007·Psychological Medicine·Louisa DegenhardtDiana McKay
May 5, 2007·Schizophrenia Bulletin·Christoph U CorrellBarbara A Cornblatt
Jul 13, 2007·Addiction·Margriet van LaarRon de Graaf
Jul 31, 2007·Lancet·Theresa H M MooreGlyn Lewis
Sep 11, 2007·The Australian and New Zealand Journal of Psychiatry·Stéphane PotvinEmmanuel Stip
Oct 26, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Francis Rodriguez BambicoGabriella Gobbi
Citations
Mar 28, 2012·Current Opinion in Psychiatry·Jagadisha ThirthalliGautham Arunachal
Jun 23, 2015·Neural Plasticity·Rafaela Torres Portugal LeiteFábio Gomes de Matos E Souza
Dec 18, 2014·Asian Journal of Psychiatry·Nopporn Tantirangsee, Sawitri Assanangkornchai
Sep 24, 2013·Psychiatry Research·Rocco Luigi PicciPier Maria Furlan
Jan 23, 2018·The Cochrane Database of Systematic Reviews·Henk S TemminghDan J Stein
May 20, 2011·Rapid Communications in Mass Spectrometry : RCM·Matteo ContiPaolo Brambilla
Jun 22, 2020·Journal of Psychiatric Research·S MaderoM Balcells