Cannabis Product Ingestions in Pediatric Patients: Ranges of Exposure, Effects, and Outcomes.

Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology
Eric E KaczorStephanie Carreiro

Abstract

Pediatric exposures to cannabis edibles have been associated with serious adverse effects, such as respiratory depression. Yet, their incidence and relationship to exposure characteristics are not well defined. We attempt to describe the temporal, demographic, and clinical characteristics of pediatric patients with edible cannabis exposures and examine the relationship between these characteristics and two clinical outcomes: need for respiratory support and hospital admission. A retrospective chart review was conducted at a single, tertiary care academic medical center covering a 28-month period. Inclusion criteria were: evaluation in the ED, age <18 years at the time of presentation, and physician documented exposure to edible cannabis. Exclusion criteria were: known or suspected co-ingestion of other substances. Thirty-two cases of edible cannabis ingestions were identified. Age <10 years was associated with bradypnea, hypertension, hospital admission, and respiratory support. Use of respiratory support was significantly associated with the presence of lethargy, bradypnea, hypercarbia, seizure, and hypertension. There was a five-fold increase in the number of pediatric edible cannabis exposures after recreational cannabis dis...Continue Reading

References

Feb 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·C H Ashton
May 29, 2013·JAMA Pediatrics·George Sam WangKennon Heard
Jul 18, 2014·Intensive Care Medicine·Sophie Le GarrecPhilippe Sachs
May 4, 2016·Journal of Medical Toxicology : Official Journal of the American College of Medical Toxicology·George Sam Wang
Jul 16, 2016·Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists·Dazhe CaoChristopher O Hoyte
Jul 28, 2016·JAMA Pediatrics·George Sam WangGenie Roosevelt
Feb 18, 2017·European Journal of Pediatrics·Isabelle ClaudetNicolas Franchitto
Sep 11, 2017·The Journal of Pediatrics·John R RichardsAimee K Moulin
Apr 4, 2018·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·George Sam WangRakesh D Mistry
Nov 5, 2019·Injury Prevention : Journal of the International Society for Child and Adolescent Injury Prevention·George Sam WangKatelyn E Hall
Nov 7, 2019·Pediatric Emergency Care·Kei U Wong, Carl R Baum
Jan 19, 2020·The Journal of Pediatrics·Jessica GrahamGeorge Sam Wang
Jul 15, 2020·Pediatrics·Sadhana DharmapuriJonathan D Klein

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