Cannabis use in people with severe mental illness: The association with physical and mental health--a cohort study. A Pharmacotherapy Monitoring and Outcome Survey study

Journal of Psychopharmacology
Jojanneke BruinsFrederike Jörg

Abstract

In the general population cannabis use is associated with better cardiometabolic outcomes. Patients with severe mental illness frequently use cannabis, but also present increased cardiometabolic risk factors. We explore the association between cannabis use and cardiometabolic risk factors in patients with severe mental illness. A total of 3169 patients with severe mental illness from a Dutch cohort were included in the study. The association of cannabis use with body mass index, waist circumference, blood pressure, cholesterol, triglycerides, glucose, glycated hemoglobin and Positive and Negative Syndrome Scale was examined with separate univariate AN(C)OVA. Changes in metabolic risk factors and Positive and Negative Syndrome Scale were examined after a follow-up interval of 9-24 months, for patients who continued, discontinued, started or were never using cannabis between the two assessments. Cannabis users at baseline had lower body mass index, smaller waist circumference, lower diastolic blood pressure, and more severe psychotic symptoms than non-users. Patients who discontinued their cannabis use after the first assessment had a greater increase in body mass index, waist circumference, diastolic blood pressure and triglycer...Continue Reading

References

Feb 1, 1992·Acta Psychiatrica Scandinavica·V Peralta, M J Cuesta
Aug 1, 1986·Psychological Medicine·J C NegreteW B Smith
Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Jul 15, 1999·Psychological Medicine·S BrownC Thompson
May 21, 2003·The Journal of Clinical Psychiatry·Murad AtmacaBilal Ustundag
Feb 1, 2005·Human Psychopharmacology·Maria IsaacFrank Holloway
Mar 3, 2005·The American Journal of Psychiatry·Nancy C AndreasenDaniel R Weinberger
Apr 28, 2005·Nature Neuroscience·Vincenzo Di Marzo, Isabel Matias
May 6, 2005·Journal of Psychopharmacology·David M SempleStephen M Lawrie
Sep 28, 2005·Journal of Addictive Diseases·Matthew WarrenMark Gold
Oct 4, 2005·The British Journal of Psychiatry : the Journal of Mental Science·Bob GreenDavid Kavanagh
Dec 13, 2005·American Heart Journal·Charles H HennekensDaniel E Casey
Aug 9, 2006·The American Journal of Cardiology·Nicolas RodondiUNKNOWN Coronary Artery Risk Development in Young Adults (CARDIA) Study
Dec 5, 2006·Trends in Endocrinology and Metabolism : TEM·Isabel Matias, Vincenzo Di Marzo
Aug 10, 2007·The Journal of Clinical Psychiatry·Jaana M SuvisaariAntti Reunanen
May 19, 2010·The American Journal of Psychiatry·Daniel J FotiEvelyn J Bromet
Jun 2, 2010·The British Journal of Psychiatry : the Journal of Mental Science·Cécile HenquetInez Myin-Germeys
Mar 8, 2011·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Marc DE HertStefan Leucht
May 17, 2011·European Psychiatry : the Journal of the Association of European Psychiatrists·D SchoepfR Heun
Jun 1, 2004·American Journal of Botany·Karl W Hillig, Paul G Mahlberg
Aug 27, 2011·American Journal of Epidemiology·Yann Le Strat, Bernard Le Foll
Sep 9, 2011·Psychological Medicine·J H MeijerUNKNOWN Genetic Risk and Outcome of Psychosis (GROUP) Investigators
Aug 22, 2012·Cold Spring Harbor Perspectives in Medicine·Erik B Oleson, Joseph F Cheer
Apr 6, 2013·Korean journal of family medicine·Ji Young KimYoon Jeong Cho
May 21, 2013·The American Journal of Medicine·Elizabeth A PennerMurray A Mittleman
Jun 6, 2013·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A DrewnowskiB Chaix
Jan 30, 2015·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Barbara J WeilandKent E Hutchison

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Citations

Aug 25, 2016·Schizophrenia Research·Edith J LiemburgUNKNOWN GROUP investigators
Dec 9, 2017·International Journal of Mental Health Nursing·Chris WagstaffLloyd Tatham
Jan 24, 2018·BMC Psychiatry·Marina ŠagudWei Wang
Feb 1, 2019·Journal of Psychopharmacology·Javier Vázquez-BourgonBenedicto Crespo-Facorro
Oct 7, 2017·The British Journal of Psychiatry : the Journal of Mental Science·Anne LooijmansEva Corpeleijn
Oct 19, 2017·Journal of Clinical Psychopharmacology·Hélène PeyrièreYves Leglise
Jul 28, 2017·European Psychiatry : the Journal of the Association of European Psychiatrists·M A IslamUNKNOWN GROUP Investigators
Feb 9, 2021·Frontiers in Psychiatry·Leah N HitchcockL Cinnamon Bidwell

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Methods Mentioned

BETA
Pharmacotherapy

Software Mentioned

PHAMOUS
SPSS Statistics

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