Cannula Tip With Integrated Volume Sensor for Rotary Blood Pump Control: Early-Stage Development

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Joshua P CysykGerson Rosenberg

Abstract

The lack of direct measurement of left ventricular unloading is a significant impediment to the development of an automatic speed control system for continuous-flow left ventricular assist devices (cf-LVADs). We have developed an inlet cannula tip for cf-LVADs with integrated electrodes for volume sensing based on conductance. Four platinum-iridium ring electrodes were installed into grooves on a cannula body constructed from polyetheretherketone (PEEK). A sinusoidal current excitation waveform (250 μA pk-pk, 50 kHz) was applied across one pair of electrodes, and the conductance-dependent voltage was sensed across the second pair of electrodes. The conductance catheter was tested in an acute ovine model (n = 3) in conjunction with the HeartMate II rotary blood pump to provide circulatory support and unload the ventricle. Echocardiography was used to measure ventricular size during pump support for verification for the conductance measurements. The conductance measurements correlated linearly with the echocardiography dimension measurements more than the full range of pump support from minimum support to suction. This cannula tip will enable the development of automatic control systems to optimize pump support based on a real-ti...Continue Reading

References

Nov 1, 1992·Medical & Biological Engineering & Computing·K R Visser
Oct 31, 2002·Artificial Organs·Edward BullisterJames Sluetz
Aug 19, 2007·IEEE Transactions on Bio-medical Engineering·Chia-Ling WeiJohn A Pearce
May 7, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Timothy J MyersO H Howard Frazier
Oct 29, 2010·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Christiane KuglerMartin Strueber
Feb 27, 2013·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Evan S LeibnerWalter E Pae
Jan 13, 2015·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Mette Holme Jung, Finn Gustafsson
Aug 5, 2015·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Raymond F StainbackUNKNOWN American Society of Echocardiography
Jun 2, 2017·Annals of Biomedical Engineering·Marianne Schmid DanersVolkmar Falk
Jun 22, 2017·The Journal of Thoracic and Cardiovascular Surgery·Stavros G DrakosTimothy J Baldwin
Sep 1, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Gregor OchsnerMarianne Schmid Daners

❮ Previous
Next ❯

Citations

Sep 15, 2019·Artificial Organs·Eric L WuShaun D Gregory
Aug 20, 2019·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Teruhiko Imamura
Sep 8, 2020·Advanced Healthcare Materials·Seraina A DualMarianne Schmid Daners
Apr 27, 2021·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Marianne Schmid DanersSeraina A Dual

❮ Previous
Next ❯

Related Concepts

Related Feeds

Artificial Heart & Ventricular Assist Devices

Total artificial hearts (TAH) and ventricular assist devices (VADs) provide cardiac support for patients with end-stage heart disease and have significantly improved the survival of these patients. Discover the latest research on Artificial Heart and Ventricular Assist Devices here.

Related Papers

Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Joshua P CysykGerson Rosenberg
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Jasmin S HankeJan D Schmitto
The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation
Kei WoldendorpChristopher S Hayward
© 2022 Meta ULC. All rights reserved