Capacity of anaerobic bacteria from necrotic dental pulps to induce purulent infections.

Infection and Immunity
G K SundqvistU T Sjögren

Abstract

Combinations of bacteria isolated from the root canals of teeth with necrotic pulps and periapical bone destruction were tested for their capacity to induce abscess formation and transmissible infections when inoculated subcutaneously into guinea pigs. Transmissible infections could be induced with combinations obtained from teeth with purulent apical inflammation, but not with combinations from symptomless teeth with chronic apical inflammation. All combinations which gave transmissible infections contained strains of Bacteroides melaninogenicus or B. asaccharolyticus (formerly B. melaninogenicus subsp. asaccharolyticus). The results suggest that purulent inflammation in the apical region in certain cases may be induced by specific combinations of bacteria in the root canal and that the presence of B. melaninogenicus or B. asaccharolyticus in such combinations is essential. However, with one exception, the strains needed the support of additional microorganisms to achieve pathogenicity. The results indicate that Peptostreptococcus micros was also essential. Histological sections of the lesions in the guinea pigs showed that all bacterial combinations induced acute inflammation with an accumulation of polymorphonuclear leukocyt...Continue Reading

References

Feb 1, 1976·Journal of Periodontal Research·B L WilliamsJ C Sherris
May 11, 1975·Journal of Endodontics·W C Wittgow, C B Sabiston
Jul 1, 1975·Journal of Endodontics·J E Vande Visse, J D Brilliant
Dec 23, 1969·Biochimica Et Biophysica Acta·E Hausmann, E Kaufman
Jan 1, 1967·Acta Pathologica Et Microbiologica Scandinavica·S E Holm
Dec 1, 1967·Archives of Oral Biology·P R Courant, R J Gibbons
Dec 1, 1969·The Journal of Infectious Diseases·D S Roberts
Nov 1, 1954·The Journal of Infectious Diseases·J B MACDONALDM L KNOLL
Jan 1, 1957·International Archives of Allergy and Applied Immunology·C WADSWORTH
Apr 1, 1961·Journal of Bacteriology·R J GIBBONS, J B MACDONALD
May 1, 1961·The Journal of Infectious Diseases·S E MERGENHAGENH W SCHERP
May 1, 1963·Archives of Oral Biology·R J GIBBONSJ B MACDONALD
Jun 1, 1965·The Journal of Infectious Diseases·S S SOCRANSKY, R J GIBBONS
Jan 1, 1962·Journal of Dental Research·J B MACDONALD, R J GIBBONS
Oct 1, 1970·Infection and Immunity·A Forsgren, U Forsum

❮ Previous
Next ❯

Citations

Mar 1, 1990·Journal of Clinical Periodontology·J O BergS Lindskog
Sep 1, 1990·International Endodontic Journal·U SjögrenG Sundqvist
Nov 1, 1989·International Endodontic Journal·M K WuP R Wesselink
Apr 1, 1987·Endodontics & Dental Traumatology·M HaapasaloH Ranta
Mar 1, 1988·Journal of Clinical Periodontology·A J van WinkelhoffJ de Graaff
Mar 1, 1982·Journal of Periodontal Research·G SundqvistE Johansson
Jan 1, 1984·Antonie van Leeuwenhoek·T J van SteenbergenJ de Graaff
Aug 1, 1993·Oral Microbiology and Immunology·H YoshimotoT Umemoto
Mar 1, 1996·International Endodontic Journal·B P GomesD B Drucker
Jul 26, 2005·Journal of Dental Research·C W KaplanS Kinder Haake
Apr 5, 2013·Clinical Microbiology Reviews·José F Siqueira, Isabela N Rôças
Feb 1, 1984·Scandinavian Journal of Dental Research·G K SundqvistA Väätäinen
Jun 1, 1982·Scandinavian Journal of Dental Research·L FabriciusA J Möller
Aug 1, 1993·Oral Microbiology and Immunology·M D PetitJ de Graaff
Sep 15, 2001·Journal of Endodontics·J F SiqueiraK R Santos
Sep 1, 1995·International Endodontic Journal·A W Brauner, G Conrads
Jun 26, 2003·International Endodontic Journal·L E Chávez De PazG Bergenholtz
Jan 5, 2006·Oral Microbiology and Immunology·G Dahlén, A Leonhardt
Oct 17, 2009·Oral Microbiology and Immunology·R FujiiK Ishihara
May 15, 2009·Clinical Implant Dentistry and Related Research·Stephen Nelson, Graham Thomas
Aug 24, 2011·Brazilian Dental Journal·Carlos EstrelaJesus Djalma Pécora
Jun 30, 2015·International Endodontic Journal·N AidaT Muramatsu
Aug 11, 1992·Oral Microbiology and Immunology·J C BaumgartnerT Beckerman
Feb 1, 1992·Oral Microbiology and Immunology·T E RamsJ Slots
Mar 1, 1988·Oral Microbiology and Immunology·S S SocranskyJ D Hillman
Aug 1, 1981·Journal of Clinical Periodontology·W H van Palenstein Helderman
Apr 20, 2001·International Endodontic Journal·C A Murray, W P Saunders
Dec 4, 2003·Journal of Endodontics·José F Siqueira, Isabela N Rôças
Jun 29, 2004·Journal of Endodontics·Samuel Seltzer, Irving J Naidorf

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.