Capillary blood glucose screening for gestational diabetes: a preliminary investigation

American Journal of Obstetrics and Gynecology
M B LandonS G Gabbe

Abstract

Home glucose monitoring with the use of reflectance meters is an important adjunct in the care of pregnant women with insulin-dependent diabetes. The accuracy of reflectance meters for the assay of capillary glucose specimens has been well documented. The present preliminary study was undertaken to determine the utility of outpatient screening for gestational diabetes mellitus with the use of a reflectance meter (Accu-Chek, Boehringer Mannheim Co.). One hundred twenty-five patients in our high-risk practice had a standard 50 gm glucose load at 26 to 28 weeks' gestation. Capillary glucose values were measured on site with the Accu-Chek. Venous plasma glucose levels were measured by the central laboratory chemistry analyzer. While the laboratory (x) and meter (y) glucose determinations between the two sets of values were highly correlated (R = 0.89, p less than 0.001), there was a significant difference in their average values (x = 111.74, y = 136.35, p less than 0.0001). With the use of a receiver operator characteristic curve, a meter value of 160 mg/dl was determined as the optimal threshold for performing a 3-hour glucose tolerance test. The sensitivity and specificity with the use of a meter value of 160 mg/dl were 93% and 9...Continue Reading

References

Jun 1, 1985·Diabetes·M B Landon, S G Gabbe
Jul 15, 1985·American Journal of Obstetrics and Gynecology·D K RichardsonS G Gabbe
Dec 15, 1985·American Journal of Obstetrics and Gynecology·G P MarquetteJ R Niebyl
Sep 1, 1984·European Journal of Obstetrics, Gynecology, and Reproductive Biology·X De Muylder
Aug 27, 1982·JAMA : the Journal of the American Medical Association·J B O'Sullivan
May 1, 1981·Diabetes Care·M L ReevesC M Peterson

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Citations

Apr 29, 2010·Current Diabetes Reports·J Seth Hawkins
Jun 1, 1991·Baillière's Clinical Obstetrics and Gynaecology·D R Coustan
Dec 16, 1997·American Journal of Obstetrics and Gynecology·A E DillonJ P VanDorsten
Jan 30, 2004·Diabetes Care·Imad M El-KebbiLawrence S Phillips
Aug 14, 2001·Clinics in Perinatology·C J Homko, E A Reece

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