PMID: 15353454Sep 9, 2004Paper

Capillary leakage in cardiac surgery with cardiopulmonary bypass

Asian Cardiovascular & Thoracic Annals
Yoshihiro HamadaHiroshi Imagawa

Abstract

Cardiopulmonary bypass causes a systemic inflammatory response, which can lead to capillary leak syndrome. In 15 adults undergoing elective cardiac surgery with cardiopulmonary bypass, we determined the volume and peak time of capillary leakage from the measurements of extracellular fluid volume and circulating blood volume taken preoperatively, at various intervals up to 24 hours after surgery, and on the 7th postoperative day. Extracellular fluid volume rose from 15.5 +/- 2.7 L preoperatively to a peak 4 hours after surgery of 18.3 +/- 3.2 L and remained elevated at 24 hours. Circulating blood volume fell from 4.10 +/- 0.68 L preoperatively to 3.20 +/- 0.58 L at the end of surgery. Fluid administered intraoperatively did not raise the circulating blood volume. Intraoperative fluid balance was positive at 2.62 +/- 0.72 L but negative at all time points postoperatively. There was significant postoperative capillary leakage, increasing from 4.7% +/- 2.3% of body weight at the end of surgery to a peak 4 hours later of 5.4% +/- 2.0% and falling to 2.8% +/- 3.3% at 24 hours. This knowledge of the pattern of change in capillary leakage after cardiac surgery with cardiopulmonary bypass might serve as a valuable guide for postoperativ...Continue Reading

References

Jan 1, 1991·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·T MaeharaM J Elliot
Dec 1, 1993·The Annals of Thoracic Surgery·N E MoatA H Finn
Jul 1, 1995·The Journal of Thoracic and Cardiovascular Surgery·J GonzalezD Wilmore
Aug 1, 1994·The American Journal of Clinical Nutrition·W D van Marken LichtenbeltS C Luijendijk
Nov 1, 1993·The Annals of Thoracic Surgery·D P TaggartD J Wheatley
Jun 1, 1996·The Annals of Thoracic Surgery·J CremerH G Borst
Sep 1, 1996·The Journal of Thoracic and Cardiovascular Surgery·M C SeghayeG Von Bernuth
Jun 6, 2000·The Journal of Thoracic and Cardiovascular Surgery·C S CoxJ Frederick

❮ Previous
Next ❯

Citations

Sep 15, 2012·Endocrine·Giovanna CapriroloHershel Raff
May 23, 2012·The Annals of Thoracic Surgery·Timothy J GeorgeGlenn J Whitman
Jul 21, 2009·La Revue de médecine interne·M Gousseff, Z Amoura
Mar 19, 2014·Acta Anaesthesiologica Scandinavica·T B EngerV Videm
Aug 1, 2006·Biochimica Et Biophysica Acta·Jonathan R EganDavid S Winlaw
Aug 23, 2016·Journal of Cardiothoracic and Vascular Anesthesia·Roberto Alberto De BlasiMonica Rocco
Oct 9, 2016·The Annals of Thoracic Surgery·Milo EngorenSachin Kheterpal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.