PMID: 8453173Mar 1, 1993Paper

Capsaicin: identification, nomenclature, and pharmacotherapy

The Annals of Pharmacotherapy
G A Cordell, O E Araujo

Abstract

To provide a brief overview of the chemical history, analysis, nomenclature, biology, pharmacology, and pharmacotherapy of capsaicin. Chemical Abstracts, Biological Abstracts, and a MEDLINE search were used to identify pertinent literature; selected literature was used in this review. Original articles, reviews, and abstracts of articles were used to select material pertinent to the objectives of the review. The volume of material available prohibits comprehensive data extraction. A history of the use of Capsicum spp. and the predominant active ingredient, capsaicin, the parent compound of a group of vanillyl fatty acid amides, is presented. Distinct structural differences are noted between this compound and the capsaicinoids, especially the synthetic analog nonivamide, which has appeared as an adulterant in capsaicin-labeled products. Analysis shows that although some of these synthetic analogs eventually may prove to be true natural products, conclusive evidence based on isolation and structure elucidation is still absent after decades of attempted isolation from several potential natural sources. Although the crude, dark oleoresin extract of capsicum contains over 100 distinct volatile compounds and therefore may function in...Continue Reading

References

Jun 1, 1988·Pain·Peter N C WatsonVerna R Watt
Jan 1, 1989·The Clinical Journal of Pain·F SicuteriM Fanciullacci
Aug 1, 1989·Journal of the American Academy of Dermatology·J E BernsteinL E Millikan
Jan 1, 1987·Critical Reviews in Food Science and Nutrition·V S GovindarajanN Chand
Feb 1, 1983·Pain·M Fitzgerald
Feb 27, 1937·British Medical Journal·T Lewis

❮ Previous
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Citations

Feb 11, 2000·Annals of the New York Academy of Sciences·T K Yun
May 15, 2001·Phytotherapy Research : PTR·G A CordellN R Farnsworth
Oct 27, 2004·Expert Opinion on Investigational Drugs·Keith R Bley
Jan 5, 2007·Spine·Joel J GagnierClaire Bombardier
Apr 25, 2007·International Journal of Toxicology·Sanjay ChandaKeith Bley
Aug 30, 2008·Applied Microbiology and Biotechnology·Seon-Mi LeeHyung Joo Suh
Aug 13, 2008·Proceedings of the National Academy of Sciences of the United States of America·Joshua J TewksburyDouglas J Levey
Sep 16, 2017·Journal of Food and Drug Analysis·Yen-Chen TungChi-Tang Ho
Jul 1, 1996·The Annals of Pharmacotherapy·W A WatsonE J Westdorp
Jul 27, 2001·Nature·J J Tewksbury, G P Nabhan
Dec 18, 2001·Journal of Applied Toxicology : JAT·E J Olajos, H Salem
Dec 13, 2002·International Journal of Cancer. Journal International Du Cancer·Hye-Jung KangAree Moon
May 24, 2006·International Journal of Toxicology·Sanjay ChandaKeith Bley
Mar 31, 2006·Journal of Chemical Ecology·Joshua J TewksburyDouglas J Levey
Aug 10, 2006·Oecologia·Douglas J LeveyTomás A Carlo
Jun 10, 2020·Scientific Reports·Marcus O W GrimmTobias Hartmann
Oct 4, 2006·Current Opinion in Anaesthesiology·A Kopf, W Ruf
Jan 19, 2006·World Journal of Gastroenterology : WJG·Yi-Ching LoDeng-Chyang Wu
Jan 14, 1999·The American Journal of Forensic Medicine and Pathology·R W Busker, H P van Helden
Sep 12, 2000·Journal of Hematotherapy & Stem Cell Research·Y LiW Ho
Oct 22, 2011·Holistic Nursing Practice·Stephanie Maxine Ross
Mar 29, 2014·Prehospital Emergency Care : Official Journal of the National Association of EMS Physicians and the National Association of State EMS Directors·Thomas KearneyCraig Smollin
Oct 19, 2010·Journal of Toxicology and Environmental Health. Part a·Kyoung Hye KongJaewon Lee
Sep 17, 2015·Journal of Forensic Sciences·Şeref Kerem ÇorbacɩoğluGökhan Aksel
Jun 30, 2015·Journal of Pharmacopuncture·Pandi AnandakumarThiruvengadam Devaki
Dec 17, 2010·Plant Cell Reports·Cesar Aza-GonzálezNeftalí Ochoa-Alejo
Nov 17, 2016·Proceedings of the National Academy of Sciences of the United States of America·Amina BouslimaniPieter C Dorrestein
Nov 10, 2013·Bioscience, Biotechnology, and Biochemistry·Su-Jung YeonChi-Ho Lee
Oct 1, 2019·Archives of Physiology and Biochemistry·Ankita ChaudharySyed Ibrahim Rizvi
Apr 1, 1997·The Annals of Pharmacotherapy·A I Jacknowitz
Apr 30, 2002·Pharmazie in unserer Zeit·Markus Veit
Jan 14, 2010·Journal of Cellular Biochemistry·Ranjan MaityNihar Ranjan Jana
Jan 9, 2008·Drug Metabolism and Disposition : the Biological Fate of Chemicals·Sanjay ChandaKeith Bley
Dec 30, 2003·BioFactors·Giuseppe Galati, Peter J O'Brien

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