Capsule endoscopy in children: which are the best indications?

Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie
C Dupont-LucasJ Viala

Abstract

Capsule endoscopy (CE) is a novel and noninvasive means of investigating the small bowel. In children, the best CE indications have not yet been fully appraised. The aim of this study was to evaluate the diagnostic yield of CE in different pediatric pathologies. We retrospectively reviewed every CE performed in children in two French pediatric hospitals between March 2002 and June 2009. Seventy-nine CEs were performed on 70 children (mean age, 10.6 years; range, 2.2-18.0); 52 boys and 18 girls. The indications were iron deficiency anemia (24%), obscure gastrointestinal bleeding (14%), polyposis syndromes (16%), suspected Crohn disease (15%), unresponsive Crohn disease (10%), graft-versus-host disease (10%), and other (10%). Of the 79 CEs, 69 reached the cecum (87%). Only one occlusion occurred in a case of stenosing Crohn disease, requiring surgical removal. In addition, technical difficulties led to an incomplete small bowel study in 12 cases (16%). The CE showed small bowel lesions in 42 cases (53%). The diagnostic yield was 27% in obscure gastrointestinal bleeding, 37% in iron-deficiency anemia, 42% in suspected Crohn disease, 88% in unresponsive Crohn disease, 62% in polyposis syndromes, and 88% in graft-versus-host disease...Continue Reading

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Citations

Apr 16, 2014·Mediators of Inflammation·Florent Malard, Mohamad Mohty
Mar 11, 2017·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·J VialaA Lachaux
May 9, 2012·Nature Reviews. Gastroenterology & Hepatology·Laurel R Fisher, William L Hasler
Oct 16, 2018·Gastroenterology Research and Practice·Yuting QianRuizhe Shen

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