PMID: 6105292Jul 19, 1980Paper

Captopril and frusemide in severe drug-resistant hypertension

Lancet
N J WhiteJ G Ledingham

Abstract

10 patients with severe refractory hypertension were treated with captopril and frusemide. All patients had uncontrolled blood pressure (mean arterial pressure > 140 mm Hg), and 7 had developed accelerated hypertension despite maximum conventional treatment. Captopril and frusemide controlled blood pressure in all 10 patients, without side effects in 9. There was a significant rise in plasma-potassium in 9 patients (1 mmol/l), and hyperkalaemia (plasma-potassium > 6 mmol/l) developed in 3 patients despite coincident treatment with frusemide.

References

Oct 20, 1979·Lancet·A B Atkinson, J I Robertson
Mar 23, 1972·The New England Journal of Medicine·R ZacestJ Koch-Weser

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Citations

Jan 1, 1981·European Journal of Clinical Pharmacology·J H de BruynM A Schalekamp
Apr 1, 1986·Klinische Wochenschrift·P GremingerW Vetter
Jan 1, 1988·Journal of General Internal Medicine·J B Reuler, G J Magarian
Oct 1, 1987·American Heart Journal·B N Prichard, B Tomlinson
Apr 17, 1982·Lancet·J D SwalesH Thurston
Jul 1, 1982·The New England Journal of Medicine
Apr 1, 1983·British Heart Journal·H J DargieJ I Robertson
Sep 1, 1994·British Heart Journal·J I Robertson
Jan 1, 1983·Clinical and Experimental Hypertension. Part A, Theory and Practice·P LijnenA Amery
Aug 1, 1984·Australian and New Zealand Journal of Medicine·C I Johnston
Nov 1, 1983·Anaesthesia and Intensive Care·C I Johnston, B Jackson
Jan 1, 1982·Scandinavian Journal of Urology and Nephrology·M AurellH Herlitz
Jan 1, 1982·British Journal of Clinical Pharmacology·J HavelkaH Vetter
Dec 1, 1981·Drug Intelligence & Clinical Pharmacy·C Harris, G H Smith
Jan 1, 1986·British Journal of Clinical Pharmacology·B N Prichard, C W Owens

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