Capturing bacterial metabolic exchange using thin film desorption electrospray ionization-imaging mass spectrometry.

Analytical Chemistry
Jeramie WatrousPieter C Dorrestein

Abstract

Over 60% of current pharmaceutical drugs have origins in natural products. To expand on current methods allowing one to characterize natural products directly from bacterial culture, herein we describe the use of desorption electrospray ionization (DESI) imaging mass spectrometry in monitoring the exchange of secondary metabolites between Bacillus subtilis and Streptomyces coelicolor using a simple imprinting technique.

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Citations

Feb 11, 2011·Analytical and Bioanalytical Chemistry·J A FernándezR Rodríguez-Puertas
Apr 6, 2011·Analytical and Bioanalytical Chemistry·Andrea PennaGiovanni Predieri
Aug 10, 2012·Journal of the American Society for Mass Spectrometry·Christian Janfelt, Asger W Nørgaard
Apr 23, 2013·Journal of the American Society for Mass Spectrometry·Elaine C CabralDemian R Ifa
Jan 4, 2013·The ISME Journal·Jeramie D WatrousPieter C Dorrestein
Aug 9, 2011·Nature Reviews. Microbiology·Jeramie D Watrous, Pieter C Dorrestein
May 16, 2012·Proceedings of the National Academy of Sciences of the United States of America·Jeramie WatrousPieter C Dorrestein
Jun 14, 2014·Antonie van Leeuwenhoek·Olga Genilloud
Jan 6, 2016·Journal of the American Society for Mass Spectrometry·Christopher R AndertonLjiljana Paša-Tolić
Nov 14, 2015·Analytical Chemistry·Julia Laskin, Ingela Lanekoff
Aug 26, 2014·Current Opinion in Biotechnology·Cheng-Chih Hsu, Pieter C Dorrestein
Sep 22, 2012·Mass Spectrometry Reviews·Chunping WuDemian R Ifa
Feb 16, 2011·Journal of Mass Spectrometry : JMS·Jeramie D WatrousPieter C Dorrestein
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