CARB-9, a carbenicillinase encoded in the VCR region of Vibrio cholerae non-O1, non-O139 belongs to a family of cassette-encoded beta-lactamases

Antimicrobial Agents and Chemotherapy
Alejandro PetroniMarcelo F Galas

Abstract

The gene bla(CARB-9) was located in the Vibrio cholerae super-integron, but in a different location relative to bla(CARB-7). CARB-9 (pI 5.2) conferred beta-lactam MICs four to eight times lower than those conferred by CARB-7, differing at Ambler's positions V97I, L124F, and T228K. Comparison of the genetic environments of all reported bla(CARB) genes indicated that the CARB enzymes constitute a family of cassette-encoded beta-lactamases.

References

May 15, 1991·The Biochemical Journal·R P AmblerS G Waley
Feb 1, 1982·Journal of Bacteriology·A A MedeirosG A Jacoby
Aug 4, 1998·Antimicrobial Agents and Chemotherapy·F SanschagrinR C Levesque
Apr 2, 1999·Antimicrobial Agents and Chemotherapy·C E Briggs, P M Fratamico
Oct 6, 2000·Microbiology·C A ClarkP A Manning
Oct 16, 2001·Antimicrobial Agents and Chemotherapy·S R PartridgeR M Hall
Apr 16, 2002·Molecular Microbiology·Dean A Rowe-MagnusDidier Mazel
Apr 18, 2002·Antimicrobial Agents and Chemotherapy·Sally R PartridgeRuth M Hall
May 23, 2003·Antimicrobial Agents and Chemotherapy·Hyunjoo PaiShukho Kim

❮ Previous
Next ❯

Citations

Jul 18, 2006·Nature Reviews. Microbiology·Didier Mazel
Jul 15, 2009·Nucleic Acids Research·Dean A Rowe-Magnus
Dec 10, 2009·Antimicrobial Agents and Chemotherapy·Karen Bush, George A Jacoby
Mar 14, 2007·Antimicrobial Agents and Chemotherapy·C C PapagiannitsisV Miriagou
May 26, 2006·Antimicrobial Agents and Chemotherapy·Liam D H Elbourne, Ruth M Hall
Aug 17, 2011·Antimicrobial Agents and Chemotherapy·Gaelle CuzonPatrice Nordmann
Aug 17, 2010·Annual Review of Genetics·Guillaume CambrayDidier Mazel
May 21, 2010·Critical Reviews in Microbiology·Wei-Hua Zhao, Zhi-Qing Hu
Jun 15, 2007·Trends in Microbiology·Yan BoucherH W Stokes
Apr 15, 2009·Environmental Microbiology·Frédérique Le RouxDidier Mazel
Oct 27, 2005·Diagnostic Microbiology and Infectious Disease·Nancy Claudia CastañedaDaniela Centrón
May 23, 2014·Microbiology and Molecular Biology Reviews : MMBR·Michael R Gillings
Mar 25, 2015·Antimicrobial Agents and Chemotherapy·Jiachi ChiouSheng Chen
Apr 11, 2019·Proceedings. Biological Sciences·Matthew J DormanNicholas R Thomson
Jan 17, 2021·International Journal of Paleopathology·Darío Alejandro RamirezRodrigo Nores

❮ Previous
Next ❯

Related Concepts

Related Feeds

CRISPR Screens in Drug Resistance

CRISPR-Cas system enables the editing of genes to create or correct mutations. This feed focuses on the application of CRISPR-Cas system in high-throughput genome-wide screens to identify genes that may confer drug resistance.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America
D A Rowe-MagnusD Mazel
Mikrobiyoloji bülteni
Ozgen Köseoğlu
Current Opinion in Microbiology
D A Rowe-Magnus, D Mazel
© 2021 Meta ULC. All rights reserved