Carbohydrates and diet patterns in nonalcoholic fatty liver disease in children and adolescents

Current Opinion in Clinical Nutrition and Metabolic Care
Ahlia SekkarieMiriam B Vos

Abstract

The primary treatment for nonalcoholic fatty liver disease (NAFLD) in children is lifestyle change, including a healthier diet. However, there are no agreed upon expert recommendations for a specific diet in the prevention or treatment of NAFLD. In this study, we review studies published between 2015 and 2017 contributing to further understanding of the role of diet in the development and progression of NAFLD, particularly those addressing sugars and dietary patterns. Multiple recent studies have expanded on earlier evidence that suggests that high intake of sugars plays a causal role in the development of NAFLD, including several recent experimental studies in adults and children that support a unique effect of fructose consumption on liver fat accumulation. Evidence also points to protective effects of dietary patterns that include but are not limited to minimizing sugar intake, Dietary Approaches to Stop Hypertension (DASH), high protein and the Mediterranean diet. The effect of diet may act through its impact on the microbiome, and may be modified by presence or absence of genetic polymorphisms (nutrigenomics) and several new studies demonstrate this. Diet appears to be a powerful tool in the prevention and treatment of NAF...Continue Reading

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Citations

Jun 15, 2018·Journal of Pediatric Gastroenterology and Nutrition·Berthold KoletzkoMartin Weber
Jan 9, 2019·Hepatology Communications·Andreia RibeiroEtienne M Sokal
Nov 14, 2019·Arquivos De Gastroenterologia·Sebastião Mauro Bezerra DuarteClaudia Pinto Marques Souza de Oliveira
Feb 17, 2019·International Journal of Environmental Research and Public Health·Pouya SaeediPaula M L Skidmore
Oct 27, 2020·Endocrinology, Diabetes & Metabolism·Eduardo Castillo-LeonMiriam B Vos
Mar 24, 2020·Gastroenterology·Dana Goldner, Joel E Lavine
May 20, 2021·European Journal of Clinical Nutrition·Luisa BonsembianteClaudio Maffeis

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