PMID: 7543298Jun 1, 1995Paper

Carbohydrates mediate the adherence of hamster sperm to oviductal epithelium

Biology of Reproduction
R P DemottS S Suarez

Abstract

The lower isthmus of the mammalian oviduct appears to serve as a reservoir for sperm that are retained by adherence to the epithelium. By inhibiting sperm binding within excised hamster oviducts and making use of carbohydrate probes, we have characterized the adherence of sperm in the reservoir and established a potential biochemical mechanism for the adherence and release of sperm. Fetuin and its terminal sugar, N-acetylneuraminic acid, interfered with the adherence of sperm to the oviductal epithelium. Labeled fetuin bound to the acrosomal region of fresh epididymal sperm, but not hyperactivated sperm, which have previously been reported to release from epithelial binding. Western blots labeled with fetuin and sialic acid-recognizing lectins identified proteins at several molecular masses that are candidates for the sperm surface component involved in adherence. Labeling of some of these candidates was reduced in samples from hyperactivated sperm. These results indicate that a sialylated oligosaccharide similar to that found on fetuin may be recognized by a sperm surface component and mediate binding to the oviductal epithelium. Release may be accomplished by loss or modification of the component during capacitation or hypera...Continue Reading

Citations

Oct 15, 1998·Molecular Reproduction and Development·S LapointeM A Sirard
Aug 8, 1998·Fertility and Sterility·G V EriksenE Ernst
Jul 17, 2001·International Journal of Andrology·M KamataH Nakagawa
Jun 20, 2002·Reproduction in Domestic Animals = Zuchthygiene·Ann Van SoomA de Kruif
Jun 20, 2002·Reproduction in Domestic Animals = Zuchthygiene·Susan S Suarez
Oct 10, 2008·Reproduction, Fertility, and Development·R E LloydW V Holt
Oct 1, 2004·Biology of Reproduction·Edita SostaricBart M Gadella
May 13, 2005·Biology of Reproduction·Mahnaz Ekhlasi-HundrieserEdda Töpfer-Petersen
May 15, 2009·Reproduction : the Official Journal of the Society for the Study of Fertility·Roberto GualtieriRiccardo Talevi
Mar 16, 2013·Animal Reproduction Science·N SrivastavaAmit Kumar
Dec 8, 2004·Reproduction : the Official Journal of the Society for the Study of Fertility·T RijsselaereA de Kruif
Oct 3, 2012·Reproduction : the Official Journal of the Society for the Study of Fertility·P CoyM Avilés
Apr 1, 2014·Animal : an International Journal of Animal Bioscience·J A McGetrickS D Carrington
Apr 16, 1998·Proceedings of the National Academy of Sciences of the United States of America·J R HagamanD A O'Brien
Jan 13, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Bart LeemansAnn Van Soom
Jan 23, 2002·Molecular Reproduction and Development·Andrea WagnerEdda Töpfer-Petersen
Jul 18, 2015·Cell and Tissue Research·Susan S Suarez
Aug 18, 2009·Theriogenology·R Talevi, R Gualtieri
Aug 18, 2009·Animal Reproduction Science·Silvana A ApichelaDora C Miceli
Aug 28, 2015·The Journal of Reproduction and Development·Paisan Tienthai
Nov 11, 2008·Reproduction in Domestic Animals = Zuchthygiene·Y KonY Monji
Oct 22, 2008·Molecular Reproduction and Development·Juan M TeijeiroPatricia E Marini
Dec 17, 2008·Reproduction in Domestic Animals = Zuchthygiene·D RathU Taylor
Oct 5, 2010·Molecular Reproduction and Development·William V Holt, Alireza Fazeli
Aug 6, 2010·Medicinal Research Reviews·Ibrahim Mustafa El-DeebSo Ha Lee
Jun 21, 2014·Reproduction in Domestic Animals = Zuchthygiene·T RijsselaereA Van Soom
Jun 16, 2004·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Riccardo Talevi, Roberto Gualtieri
Oct 13, 2006·Animal Reproduction Science·Khalida Sabeur, Barry A Ball
Sep 19, 2015·Reproduction in Domestic Animals = Zuchthygiene·S Kölle
Jul 15, 2015·Zygote : the Biology of Gametes and Early Embryos·Ronald Henry Fraser Hunter, Joaquín Gadea
Mar 25, 2015·Insect Biochemistry and Molecular Biology·Kimberly StephensRichard A Cardullo
Oct 5, 2007·Maturitas·Gherardo GheriEleonora Sgambati
Nov 1, 2016·Reproduction : the Official Journal of the Society for the Study of Fertility·Bart LeemansAnn Van Soom

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