PMID: 1592679Apr 1, 1992

Carbon catabolite regulation of gentamicin formation

The Journal of Antibiotics
L EscalanteS Sanchez

Abstract

The effect of utilizable carbon sources on the production of gentamicin by Micromonospora purpurea has been studied. High D-glucose and D-xylose concentrations (40 mg/ml), exerted a strong and permanent negative action on antibiotic formation. On the other hand, similar concentrations of D-fructose, D-mannose, maltose and starch caused no effect. The glucose action is seen only if added during the logarithmic growth phase; moreover, the sugar needs to be metabolized to show its negative effect.

Citations

Feb 6, 2008·Journal of Basic Microbiology·Himabindu MeenavilliAnnapurna Jetty
Oct 22, 2008·Critical Reviews in Biotechnology·C Ganesh KumarAnnapurna Jetty
Mar 10, 2010·Critical Reviews in Microbiology·Beatriz RuizElizabeth Langley
Jul 29, 2010·The Journal of Antibiotics·Sergio SánchezBeatriz Ruiz
Jun 11, 2015·Jundishapur Journal of Microbiology·Ahmad Siti JunaidahNoraziah Mohamad Zin
Dec 1, 2008·Indian Journal of Microbiology·Renu SolankiRup Lal

Related Concepts

Gentacycol
Glucose, (beta-D)-Isomer
Fungus Drug Sensitivity Tests
Microbiological Techniques
Micromonospora
Xylose
Carbohydrate Metabolism

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