PMID: 7334898Jan 1, 1980Paper

Carbon dioxide laser therapy of cervical intraepithelial neoplasia: factors determining success rate

Lasers in Surgery and Medicine
L BurkeD Antonioli

Abstract

Sixty patients with biopsy proven CIN were treated with CO2 laser. Severity of the lesion was equally divided among all three grades of CIN. All patients were biopsied immediately after laser therapy and at six and twelve weeks past treatment. Persistence or absence of disease was evaluated with respect to severity of disease, size of lesion, method of applying laser, whether the endocervical canal was involved, whether only the lesion or the entire transformation zone was lasered, and depth of laser effect. The persistence of disease was 36.7 percent after therapy. Success was not related to severity of disease, size of lesion, or whether the endocervical canal was involved. It was related to depth of coagulation necrosis, method of applying the laser bean, and if the entire transformation zone was treated.

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Citations

Jan 4, 1992·Journal of Gynecologic Surgery·W C Sokoll, W T Creasman
Oct 20, 2006·Journal of Lower Genital Tract Disease·Thomas C WrightUNKNOWN 2001 ASCCP-sponsored Consensus Workshop
Oct 6, 2007·Journal of Lower Genital Tract Disease·Thomas C WrightUNKNOWN 2006 American Society for Colposcopy and Cervical Pathology-sponsored Consensus Conference
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Jan 1, 1984·Lasers in Surgery and Medicine·V C Wright
Jan 1, 1985·Lasers in Surgery and Medicine·J H BellinaJ D Jackson
Sep 1, 1982·The British Journal of Dermatology·J A Carruth
Jul 16, 2003·American Journal of Obstetrics and Gynecology·Thomas C WrightUNKNOWN American Society for Colposcopy and Cervical Pathology
Jan 1, 1986·Lasers in Surgery and Medicine·M S Baggish
Jan 2, 2003·Obstetrics and Gynecology Clinics of North America·J Thomas Cox

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