Carbon dioxide laser treatment for Hailey-Hailey disease: a retrospective chart review with patient-reported outcomes

International Journal of Dermatology
Phillip C HochwaltChristian L Baum

Abstract

Hailey-Hailey disease (HHD) is an autosomal dominant genodermatosis that leads to skin breakdown and blister formation, usually in intertriginous areas. Laser ablation is a known surgical treatment for HHD. We report outcomes in a series of patients with HHD treated with carbon dioxide (CO2 ) laser ablation. A retrospective chart review of data for 13 patients who underwent CO2 laser ablation for HHD was conducted. Questionnaires assessing effectiveness, pain, healing time, recurrence, new disease, complications, additional ablation, improvement in quality of life (QoL), and overall satisfaction were completed by all patients. All patients had been recalcitrant to previous treatments prior to CO2 laser ablation. Anatomic sites treated and anesthesia techniques for the procedure varied. The mean ± standard deviation (SD) score for the effectiveness of CO2 laser ablation for HHD was 9.3 ± 0.9 (maximum: 10). All patients reported improved QoL. No patient had recurring disease within the treatment field. Five patients underwent additional CO2 laser treatments at new sites. One patient reported postoperative infection. No other complications were identified. The mean ± SD score for overall satisfaction with CO2 laser ablation was 8....Continue Reading

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Citations

Oct 18, 2016·Journal of the American Academy of Dermatology·Benjamin FarahnikDirk M Elston
Oct 31, 2018·Giornale Italiano Di Dermatologia E Venereologia : Organo Ufficiale, Società Italiana Di Dermatologia E Sifilografia·Alisen HuangJared Jagdeo
Oct 9, 2019·American Journal of Clinical Dermatology·Imene Ben LaghaAmor Khachemoune
Dec 1, 2017·Anais Brasileiros De Dermatologia·Ana Iglesias PlazaNoelia Pérez Muñoz

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