Carbon dioxide therapy and hyaluronic acid for cosmetic correction of the nasolabial folds

Journal of Cosmetic Dermatology
Giuseppe NisiCarlo D'Aniello

Abstract

The main application of hyaluronic acid filling, in esthetic medicine, is the augmentation of soft tissues. The carbon dioxide therapy, instead, improves quality and elasticity of the dermis and increases the oxygen release to the tissue through an enhancing of the Bohr's effect. The aim of the study was to compare the efficacy, tolerability, and effect duration of hyaluronic acid fillers and the use of carbon dioxide therapy plus hyaluronic acid in the cosmetic correction of nasolabial folds. Forty healthy female patients received a blinded and randomized treatment on nasolabial folds (hyaluronic acid in group A and hyaluronic acid plus subcutaneous injections of carbon dioxide in group B) for cosmetic correction of the nasolabial folds. The results were evaluated by two blinded plastic surgeons after the implant (1 week, 4 and 6 months) using a 1-5 graduated scale (GAIS), and at the same time, each patient was asked to express her opinion about the cosmetic result. Any long-term adverse reaction was reported. The blinded evaluation at 4 and 6 months from the implant shows in all patients a maintenance of a good cosmetic result higher for the side treated with carbon dioxide therapy plus hyaluronic acid. At the control visit, ...Continue Reading

References

Feb 26, 2004·American Journal of Clinical Dermatology·Doris J DayScott Gottlieb
Jul 25, 2008·The Journal of Craniofacial Surgery·Johannes Hönig
Jan 30, 2010·Aesthetic Plastic Surgery·Georgia S K Lee
May 14, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Matteo CampanaCarlo D'Aniello
Sep 4, 2012·Journal of Cosmetic Dermatology·Fioramonti PaoloScuderi Nicolò
May 25, 2013·Acta Cirúrgica Brasileira·Maria Vitória Carmo PenhavelJoão Batista de Sousa
Nov 10, 2013·European Journal of Dermatology : EJD·Xiaolu HuangQingfeng Li
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Nov 22, 2014·Plastic and Reconstructive Surgery·Sumit PaliwalDarin J Messina

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Citations

Feb 8, 2019·Plastic and Reconstructive Surgery·Roberto CuomoGiuseppe Nisi
Jan 16, 2018·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Roberto CuomoGiuseppe Nisi
Nov 3, 2017·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Roberto CuomoCarlo D'Aniello
Aug 19, 2016·Plastic and Reconstructive Surgery·Andrea SistiGiuseppe Nisi
Nov 6, 2018·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Roberto CuomoCarlo D'Aniello
Feb 25, 2020·Journal of Cosmetic Dermatology·Suellen Matos Domingos OliveiraAdriana Clemente Mendonça
Jul 25, 2020·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Roberto CuomoLuca Grimaldi
Apr 23, 2020·Journal of Cosmetic Dermatology·Dong Hye SuhKye Young Song

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