Carbon monoxide production and reticulocyte count in normal women. Effect of contraceptive drugs and smoking.

Acta Medica Scandinavica
C MerckeB Lundh

Abstract

Endogenous production of carbon monoxide (VCO), serum bilirubin (SB) and reticulocyte (retic) count have been followed during the menstrual cycle in 12 women (4 of them smokers) without contraceptive drugs and in 10 women (5 of them smokers) on contraceptive drugs. During the progesterone phase (Pph), VCO in the non-smokers was 18.2 +/- 2.1 mumol/mmol total body heme (TBH) and day (mean +/- 1 S.E.M.), compared with 10.1 +/- 1.0 during the estrogen phase (Eph). In the smokers, VCO was 10.4 +/- 1.9 during Pph and 12.5 +/- 0.7 during Eph. SB for the non-smokers was 5.2+/- 1.0 mug/ml during Pph and 3.9 +/- 0.5 during Eph, compared with 3.2 +/- 0.8 and 3.9 +/- 1.2, respectively, for smokers. The retic count for the non-smokers was 64.1 +/- 4.7 times 10(3)/mul during Pph and 17.7 +/- 5.1 during Eph. In the smokers the corresponding counts were 93.6 +/- 15.9 and 60.8 +/- 7.6. These results confirm earlier reports that VCO is increased during Pph and indicate that the rise could be due to a change in red cell catabolism, since it is concomitant with a significant increase in retic counts, which has not been found in earlier works on VCO, but which is known from reticulocyte studies. Furthermore, the results may indicate that persistent...Continue Reading

References

Dec 1, 1972·Scandinavian Journal of Clinical and Laboratory Investigation·B LundhE Cavallin-Stahl
Aug 1, 1973·The Journal of Obstetrics and Gynaecology of the British Commonwealth·M DavisR Williams
Jan 1, 1974·Clinical Pharmacology and Therapeutics·D E CarterM W Heine
Jan 1, 1974·Clinical Pharmacology and Therapeutics·E J PantuckA H Conney
Jan 1, 1974·Journal of Applied Physiology·M Delivoria-PapadopoulosR E Forster
Jan 1, 1972·Transfusion·F DeVenuto, S M Wilson
Sep 1, 1972·Annals of Internal Medicine·F A OskiE D Buchert
Feb 1, 1971·Metabolism: Clinical and Experimental·T R TephlyJ Baron
Jun 1, 1971·Scandinavian Journal of Clinical and Laboratory Investigation·M CeleginG Sundström
Apr 1, 1966·The Journal of Clinical Investigation·R F CoburnS B Kahn
Jan 1, 1958·Scandinavian Journal of Clinical and Laboratory Investigation·S E BJORKMAN
Jul 1, 1963·The Journal of Clinical Investigation·R F COBURNR E FORSTER

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Citations

Dec 1, 1981·Research Quarterly for Exercise and Sport·J L PuhlS J Kruse
Dec 1, 1984·European Journal of Clinical Investigation·J LindahlR Lerner

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