Carbon Nanotubes Encapsulated in Coiled-Coil Peptide Barrels

Chemistry : a European Journal
Florian A MannSebastian Kruss

Abstract

Specific functionalization of 1D nanomaterials such as near infrared (nIR) fluorescent single-walled carbon nanotubes (SWCNTs) is essential for colloidal stability and tailoring of their interactions with the environment. Here, we show that de novo designed alpha-helical coiled-coil peptide barrels (αHBs) with appropriate pores encapsulate and solubilize SWCNTs. In contrast, barrels without or with narrow pores showed a much smaller efficiency. Absorption/fluorescence spectroscopy and atomic force microscopy indicate that the SWCNTs are incorporated into the αHB's pore. The resulting hybrid SWCNT@αHBs display periodic surface coverage with a 40 nm pitch and remain fluorescent in the nIR. This approach presents a novel concept to encapsulate, discriminate and functionalize SWCNTs non-covalently with peptides and holds great promise for future applications in bioimaging or drug delivery.

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Citations

Aug 10, 2018·Chemistry : a European Journal·W Mathis Rink, Franziska Thomas
May 22, 2019·Angewandte Chemie·Florian A MannSebastian Kruss
Jul 10, 2020·ChemPlusChem·Meshkat DinarvandSebastian Kruss
Mar 22, 2020·Nature Communications·Gabriele SelvaggioSebastian Kruss
Aug 17, 2019·Chemical Society Reviews·Sofía Mena-Hernando, Emilio M Pérez
Dec 20, 2019·Chemical Science·Mingyang JiJon R Parquette
Oct 13, 2018·Chemical Science·Leire de Juan-FernándezDirk M Guldi
Oct 22, 2019·Frontiers in Immunology·Luise ErpenbeckSebastian Kruss
Nov 27, 2020·Nature Communications·Robert NißlerSebastian Kruss
Apr 9, 2021·Analytical Chemistry·Robert NißlerSebastian Kruss
Aug 17, 2019·Nano Letters·Meshkat DinarvandSebastian Kruss
May 1, 2018·ACS Applied Materials & Interfaces·Elena PoloSebastian Kruss

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