Carbon nanotubes implanted manganese-based MOFs for simultaneous detection of biomolecules in body fluids

The Analyst
Min-Qiang WangMao-wen Xu

Abstract

Metal-organic frameworks (MOFs) have recently attracted much interest in electrochemical fields due to their controlled porosity, large internal surface area, and countless structural topologies. However, the direct application of single component MOFs is limited since they also exhibit poor electronic conductivity, low mechanical stability, and inferior electrocatalytic ability. To overcome these problems, we implanted multi-walled carbon nanotubes (MWCNTs) into manganese-based metal-organic frameworks (Mn-BDC) using a one-step solvothermal method and found that the introduction of MWCNTs can initiate the splitting of bulky Mn-BDC into thin layers. This splitting is highly significant in that it enhances the electronic conductivity and electrocatalytic ability of Mn-BDC. The constructed Mn-BDC@MWCNT composites were utilized as an electrode modifying material in the fabrication of an electrochemical sensor and then were used successfully for the determination of biomolecules in human body fluid. The sensor displayed successful detection performance with wide linear detection ranges (0.1-1150, 0.01-500, and 0.02-1100 μM for AA, DA and UA, respectively) and low limits of detection (0.01, 0.002, and 0.005 μM for AA, DA and UA, res...Continue Reading

References

Feb 3, 2005·Journal of the American Chemical Society·Nathaniel L RosiOmar M Yaghi
May 8, 2014·ACS Applied Materials & Interfaces·Miao XuLing Zang
Jun 7, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Pengbo GaiJinhua Chen

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Citations

Dec 5, 2017·Dalton Transactions : an International Journal of Inorganic Chemistry·Haotian PiWeitao Zheng
Mar 7, 2018·Advanced Healthcare Materials·Jingrong ZhouXiu-Wu Bian
Jan 26, 2018·Dalton Transactions : an International Journal of Inorganic Chemistry·Wei Chen, Chunsheng Wu
Apr 7, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Yue ChengYan Li
Dec 24, 2019·Seminars in Cancer Biology·Mohammed Razeeth Shait MohammedMohammad Imran Khan

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