PMID: 2114323Jul 2, 1990Paper

Carbonic anhydrase inhibition and calcium transients in soleus fibers

FEBS Letters
Petra WetzelGerolf Gros

Abstract

We simultaneously measured cytoplasmic Ca2+ transients using Fura-2 and isometric force in rat soleus fiber bundles. In the presence of the carbonic anhydrase inhibitor, chlorzolamide, we observed a decreased amplitude and retarded decay of the Ca2+ signal. This corresponded with a decreased isometric force and a retarded muscle relaxation. We conclude that muscle carbonic anhydrase participates in excitation-contraction coupling, possibly by rapidly providing protons that are exchanged for Ca2+ across the sarcoplasmic reticulum membrane.

References

Jun 1, 1990·Archives of Biochemistry and Biophysics·P Wetzel, G Gros
Aug 1, 1985·Journal of Applied Physiology·C GeersA Gärtner
Feb 1, 1986·The Journal of Physiology·W BrunsG Gros
Jan 1, 1988·Annual Review of Physiology·G Gros, S J Dodgson
Feb 1, 1985·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·R DermietzelG Gros
Dec 1, 1982·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·D A RileyJ Bain
Apr 1, 1980·Archives of Biochemistry and Biophysics·V M Madeira
Aug 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·V ShoshanD S Wood
Mar 1, 1984·The Biochemical Journal·A ShielsN Carter

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Citations

Dec 9, 1997·Muscle & Nerve·W F BrechueJ M Stager
Oct 1, 1996·Histochemistry and Cell Biology·B DeckerG Gros
Sep 1, 1995·Comparative Biochemistry and Physiology. Part A, Physiology·C GeersG Gros
Oct 29, 2004·Molecular and Cellular Biology·Geumsoo KimRodney L Levine
Apr 15, 1997·Proceedings of the National Academy of Sciences of the United States of America·H P KubisG Gros
Jun 20, 1998·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·S SenderG Gros
Sep 13, 2002·American Journal of Physiology. Cell Physiology·Petra WetzelGerolf Gros
Apr 4, 2000·Physiological Reviews·C Geers, G Gros
Feb 10, 1999·The American Journal of Physiology·C H CôtéG Perreault
Aug 15, 1998·Archives of Biochemistry and Biophysics·P Wetzel, G Gros

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