Carcinogenesis in prostate cancer: The role of long non-coding RNAs

Non-coding RNA Research
John AirdSteven G Gray

Abstract

LncRNAs appear to play a considerable role in tumourigenesis through regulating key processes in cancer cells such as proliferative signalling, replicative immortality, invasion and metastasis, evasion of growth suppressors, induction of angiogenesis and resistance to apoptosis. LncRNAs have been reported to play a role in prostate cancer, particularly in regulating the androgen receptor signalling pathway. In this review article, we summarise the role of 34 lncRNAs in prostate cancer with a particular focus on their role in the androgen receptor signalling pathway and the epithelial to mesenchymal transition pathway.

Citations

Dec 19, 2018·Current Opinion in Oncology·Nabila BerabezMathieu Gabut
May 24, 2020·The Anatomical Record : Advances in Integrative Anatomy and Evolutionary Biology·Zeping HanYuguang Li
Dec 10, 2020·Cancer Cell International·Shengyang GeChuanyu Sun
Mar 28, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Hui-Yi LinJong Y Park
Jan 10, 2021·Seminars in Cancer Biology·Imran AnsariSaurabh Singh
Jun 30, 2019·Pathology, Research and Practice·Gulimire NaizhaerPing Zhou
Dec 5, 2020·Seminars in Cancer Biology·Shahnawaz RehmanMohd Farhan

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Methods Mentioned

BETA
ubiquitination
xenografts
xenograft

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