Carcinoid tumor of the esophagus: a clinicopathologic study of four cases

The American Journal of Surgical Pathology
Mai P HoangJ Albores-Saavedra

Abstract

Several case reports have emphasized that esophageal carcinoid tumors are associated with a poor prognosis. To expand our knowledge about the pathology and biologic behavior of these rare tumors, we reviewed the clinicopathologic and immunohistochemical findings of four cases of primary esophageal carcinoid. The age of the patients ranged from 48 to 82 years (mean 63 years; median 61 years). The lower segment of the esophagus was involved in two cases and the mid segment was involved in one case. The sizes of the tumors ranged from 0.3 cm to 3.5 cm. Two tumors were confined to the lamina propria and two invaded into the muscular wall. Two tumors appeared polypoid, whereas the remaining two were incidental findings and associated with adenocarcinoma arising in a background of Barrett esophagus. The adenocarcinoma was superficially invasive in one case, whereas it penetrated the muscular wall in the other. All four carcinoid tumors were immunoreactive with chromogranin and synaptophysin. There was focal expression of serotonin in two cases, glucagon in one case, and pancreatic polypeptide in one case. Endocrine cell hyperplasia was noted in both the Barrett esophagus and the invasive adenocarcinoma. One patient died secondary to ...Continue Reading

References

Apr 17, 1978·Virchows Archiv. A, Pathological Anatomy and Histology·B Kaduk, H Barth
Jan 1, 1991·Thorax·A SiegalM Aronheim
Jul 1, 1989·Thorax·A R ReadyH R Matthews
Jul 1, 1985·The Journal of Pathology·A M BuchanH J Freeman
Aug 1, 1987·Histopathology·I M Nawroz
Jul 1, 1986·Histopathology·A Siegal, A Swartz
Jul 1, 1980·Scottish Medical Journal·R RankinM K Browne
Dec 1, 1994·Journal of Clinical Gastroenterology·R S BrownG Taylor
Jun 15, 1994·Cancer·S Y LawJ Wong
Feb 15, 1997·Cancer·I M Modlin, A Sandor
Aug 27, 1998·Journal of Gastroenterology·S TanidaH Inagaki

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Citations

Jun 2, 2015·Archives of Pathology & Laboratory Medicine·Andrea Grin, Catherine J Streutker
Oct 28, 2016·Annals of the New York Academy of Sciences·Monika Tripathi, Paul E Swanson
Aug 11, 2020·World Journal of Gastroenterology : WJG·Gianluca BusinelloMatteo Fassan
May 26, 2006·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·D TomasB Kruslin
Jan 20, 2007·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Angela D Levy, Leslie H Sobin
Nov 24, 2016·Abdominal Radiology·Yehia M ElGuindyKhaled M Elsayes
Aug 9, 2017·World Journal of Gastroenterology : WJG·Cemal Yazici, Brian R Boulay
Jan 20, 2011·Journal of Computer Assisted Tomography·Khaled M ElsayesTravis J Hillen
Nov 23, 2016·The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·Myung Hee KimDuk Ki Kim
Jan 27, 2006·World Journal of Gastroenterology : WJG·Seng-Kee ChuahHock-Liew Eng
Feb 5, 2019·Diseases of the Esophagus : Official Journal of the International Society for Diseases of the Esophagus·G ZhangJ Li
Aug 9, 2007·Virchows Archiv : an International Journal of Pathology·Günter KlöppelPaul Komminoth
Jul 12, 2013·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Rachel B LewisMarc S Levine
Dec 13, 2017·Journal of Gastrointestinal Cancer·Constantinos SavvaSrinivasan Madhusudan
Apr 10, 2020·Archives of Pathology & Laboratory Medicine·Deepika SavantZhaohai Yang

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