Feb 1, 1976

Carcinoid tumors of the thymus

W R SalyerJ C Eggleston


Three patients with carcinoid tumors of the anterior mediastinum are described. Study of these patients and an analysis of previously reported cases indicates that the thymus is the primary site of these tumors, which are probably related to the presence of Kulchitsky cells in normal thymus. These neoplasms differ clinically and anatomically from conventional thymomas. They occur predominantly in men, are not associated with myasthenia gravis or red-cell hypoplasia, and are more aggressive tumors than thymomas. Histologically, they are similar to carcinoid tumors of other organs and differ from the variable combination of epithelial cells and lymphocytes of thymomas. Although they are usually locally invasive and frequently metastasize, the clinical course is usually protracted. It is probable that the reported examples of Cushing's syndrome related to thymomas were actually associated with thymic carcinoid tumors.

Mentioned in this Paper

Entire Anterior Mediastinum
Carcinoid Tumor
Mediastinal Neoplasms
Lymphocytes as Percentage of Blood Leukocytes (Lab Test)
Neoplasm of Uncertain or Unknown Behavior of Thymus
Squamous Transitional Epithelial Cell Count
Disease of Thymus Gland
Red Cell Phospholipid Defect With Hemolysis

About this Paper

Related Feeds

Autoimmune Polyendocrine Syndromes

This feed focuses on a rare genetic condition called Autoimmune Polyendocrine Syndromes, which are characterized by autoantibodies against multiple endocrine organs. This can lead to Type I Diabetes.

Related Papers

The Annals of Thoracic Surgery
T MizunoK Ito
Pathology, Research and Practice
M R Wick, J Rosai
Journal of the National Comprehensive Cancer Network : JNCCN
David S EttingerNational Comprehensive Cancer Network
© 2020 Meta ULC. All rights reserved