Carcinoma-associated retinopathy-an electrophysiological and immunohistochemical correlation

Retina
Barbara LinkAnselm Jünemann

Abstract

To correlate the clinical, electrophysiological, and immunohistochemical findings in patients suffering from carcinoma-associated retinopathy. Four patients with visual loss were included in this retrospective, observational consecutive case series. Electrophysiology and immunohistochemical analysis were performed to confirm the diagnosis of carcinoma-associated retinopathy. Immunohistochemistry revealed a marked interindividual variability of antibody reactions against different retinal cell layers of individual patients. The electrophysiological changes corresponded to the respective immunohistochemical findings. Carcinoma-associated retinopathy is a heterogeneous disease, caused by different antiretinal antibodies and leading to different electrophysiological abnormalities. Diagnosis should not be delayed as undetected and thus untreated malignancy can be the cause.

References

Mar 7, 2000·Klinische Monatsblätter für Augenheilkunde·B SobottkaE Zrenner
Feb 25, 2003·Advances in Experimental Medicine and Biology·Hiroshi Ohguro, Mitsuru Nakazawa
Apr 16, 2004·Lung Cancer : Journal of the International Association for the Study of Lung Cancer·Alexandr V BazhinPavel P Philippov
Jun 8, 2004·BMC Ophthalmology·Grazyna AdamusRichard G Weleber
Jun 9, 2004·American Journal of Ophthalmology·Hiroshi OhguroMitsuru Nakazawa
Apr 6, 2005·American Journal of Ophthalmology·Corinne DotGrazyna Adamus
May 18, 2006·Klinische Monatsblätter für Augenheilkunde·A KoestingerF-X Borruat
Aug 28, 2007·Documenta Ophthalmologica. Advances in Ophthalmology·Griet GoetgebuerBart P Leroy

❮ Previous
Next ❯

Citations

Apr 16, 2010·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·T HagerB Seitz
Sep 1, 2014·Journal of AAPOS : the Official Publication of the American Association for Pediatric Ophthalmology and Strabismus·Kiran TurakaChristin Sylvester
Oct 9, 2013·Current Opinion in Ophthalmology·Didar U ComlekogluH Nida Sen
Aug 1, 2012·Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde·T BraithwaiteA Tufail
Jan 18, 2018·International Journal of Retina and Vitreous·Aristófanes Mendonça CanamaryJuliana Maria Ferraz Sallum
Aug 23, 2020·Indian Journal of Ophthalmology·Parthopratim Dutta MajumderAniruddha Agarwal

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Documenta Ophthalmologica. Advances in Ophthalmology
B A van der Pol, J T Planten
Ophthalmology
C E ThirkillJ L Keltner
Lung Cancer : Journal of the International Association for the Study of Lung Cancer
S MatsubaraJ Takahara
© 2022 Meta ULC. All rights reserved