Carcinoma in situ of the cervix and its malignant potential. A lesson from New Zealand

Cytopathology : Official Journal of the British Society for Clinical Cytology
A R Chang

Abstract

An overview of studies attempting to define the natural history of carcinoma in situ of the cervix suggests that 20-30% of lesions progress to invasive carcinoma within 5-10 years. This risk of invasion and the inability to predict when invasion might occur has been reinforced by a judicial enquiry in New Zealand so that protocols that include withholding treatment are no longer justifiable. Once a diagnosis of cervical carcinoma in situ is established appropriate treatment is mandatory.

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