Carcinoma of the vulva

Obstetrics and Gynecology
Frederick B Stehman, Katherine Y Look

Abstract

The objective of this review is to summarize the published data about squamous carcinoma of the vulva and to identify promising areas for future investigation. Rather than the routine use of complete radical vulvectomy, a radical wide excision of the vulvar lesion to achieve at least a 1-cm gross margin appears sufficient to treat the primary lesion. A surgical assessment of the groin is required for all patients who have invasion greater than 1 mm. Ipsilateral groin node dissection can be performed through a separate incision. All the nodal tissue medial to the vessels and above the fascia should be removed. Sentinel node evaluation may be a significant step forward, but the false-negative rate is not well enough defined to consider this a standard. Patients with positive inguinal nodes at groin dissection should receive radiation therapy to the ipsilateral groin and hemipelvis. For those patients who have unresectable primary disease or if nodes are palpably suspicious, fixed, and/or ulcerated preoperatively, chemoradiation is the preferred option. Exenterative procedures may rarely be required. Chemotherapy for recurrent or metastatic disease has not been proven to be of value. Although survival rates are high for those with...Continue Reading

References

Jun 1, 1979·Gynecologic Oncology·G DeppeH W Bruckner
Apr 1, 1979·American Journal of Obstetrics and Gynecology·P J DiSaiaW M Rich
Apr 1, 1979·Gynecologic Oncology·S C BallonL D Lagasse
Mar 1, 1978·Obstetrics and Gynecology·R YazigiY Tsukada
Apr 15, 1976·American Journal of Obstetrics and Gynecology·G W Morley
Aug 1, 1992·Current Opinion in Obstetrics & Gynecology·R J KurmanK V Shah
Nov 1, 1992·American Journal of Obstetrics and Gynecology·A S TilmansN B Hornback
Dec 15, 1992·Cancer·M P Hopkins, G W Morley
Jan 1, 1992·International Journal of Radiation Oncology, Biology, Physics·F B StehmanP B Heller
Apr 1, 1992·Archives of Surgery·D L MortonA J Cochran
May 1, 1992·American Journal of Obstetrics and Gynecology·S R SturgeonR J Kurman
Jul 1, 1991·Gynecologic Oncology·G M ThomasA D DePetrillo
Sep 1, 1991·Gynecologic Oncology·F N RutledgeE Silva
May 1, 1991·American Journal of Obstetrics and Gynecology·W S RobertsD Cavanagh
Jun 1, 1991·American Journal of Obstetrics and Gynecology·G P SuttonC E Ehrlich
Sep 1, 1990·American Journal of Obstetrics and Gynecology·D CavanaghD P Barton
Sep 1, 1989·Gynecologic Oncology·G ThomasA Fyles
Nov 1, 1989·Gynecologic Oncology·M S HoffmanD Cavanagh
Jan 1, 1988·Gynecologic Oncology·R KürzlJ Zander
Sep 1, 1988·Gynecologic Oncology·W ChafeE Wilkinson
Sep 1, 1988·Gynecologic Oncology·K C RowleyE J Pavlik
Sep 1, 1988·American Journal of Obstetrics and Gynecology·M O BurrellD W Stacy
May 1, 1987·American Journal of Obstetrics and Gynecology·A SedlisC Whitney
Feb 1, 1986·Gynecologic Oncology·J MalfetanoY Tsukada
Mar 1, 1985·Gynecologic Oncology·J BoyceJ C Remy
Jun 15, 1985·American Journal of Obstetrics and Gynecology·D C FiggeB E Greer
Nov 1, 1985·Gynecologic Oncology·B Andreasson, J Nyboe
Jan 15, 1974·American Journal of Obstetrics and Gynecology·J T WhartonF N Rutledge
Jun 1, 1974·American Journal of Obstetrics and Gynecology·D C Figge, R Gaudenz
Apr 15, 1970·American Journal of Obstetrics and Gynecology·F RutledgeE W Franklin
Jan 1, 1984·Acta Radiologica. Oncology·E Simonsen
Jun 1, 1984·International Journal of Radiation Oncology, Biology, Physics·R H HendersonR R Million
Mar 1, 1984·Gynecologic Oncology·E ErikssonL E Peterson
Feb 1, 1983·Gynecologic Oncology·N F HackerL D Lagasse

❮ Previous
Next ❯

Citations

Sep 13, 2011·Archives of Gynecology and Obstetrics·C DittmerM Thill
Dec 25, 2012·Archives of Gynecology and Obstetrics·Jacek J SznurkowskiJanusz Emerich
Feb 23, 2010·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Lars-Christian Horn, Stefan Wagner
Dec 13, 2006·Journal of Clinical Pathology·R HolmJ M Nesland
Oct 4, 2011·Diagnostic Pathology·Marco PetrilloGabriella Ferrandina
Jun 26, 2013·AJR. American Journal of Roentgenology·Kyung Won KimNikhil H Ramaiya
May 25, 2013·AJR. American Journal of Roentgenology·Chitra ViswanathanPriya Bhosale
Aug 7, 2013·Indian Journal of Dermatology·Ana I LorenteJ Conejo-Mir
Nov 2, 2014·Seminars in Nuclear Medicine·Paul GrantHeather A Jacene
Jul 16, 2010·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·M Höckel
Oct 22, 2011·Critical Reviews in Oncology/hematology·Angiolo GadducciAndrea Riccardo Genazzani
Oct 1, 2010·PET Clinics·Priya BhosaleDonald Podoloff
Oct 24, 2007·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Filippo BellatiMarianna Nuti
Jun 8, 2012·Journal of Clinical Nursing·Hilary Jefferies, Collette Clifford
Mar 10, 2016·Current Medical Research and Opinion·Jinhong Zhou, Guoping Shan
Apr 17, 2012·Gynecologic Oncology·Josko ZekanLeila Mitrovic
Apr 21, 2012·Gynecologic Oncology·Menke H HazewinkelJan-Paul W R Roovers
Sep 5, 2008·Gynecologic Oncology·Whitfield B GrowdonBo R Rueda
Mar 17, 2009·American Journal of Obstetrics and Gynecology·Grainger S LanneauPatricia L Judson
Jul 8, 2011·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Linn WoelberSven Mahner
May 18, 2010·Gynecologic Oncology·Heidi J Gray
Oct 12, 2018·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Linda J Rogers, Mauricio A Cuello
Oct 10, 2009·Cancer Nursing·Hilary Jefferies, Collette Clifford
Apr 15, 2011·The Cochrane Database of Systematic Reviews·T S ShylasreeRobert Ej Howells
Apr 14, 2016·Molecular and Clinical Oncology·Yanxia SuiQiling Li
Aug 4, 2020·Minerva ginecologica·Salvatore LopezFrancesco Raspagliesi
Oct 22, 2019·Seminars in Nuclear Medicine·Aoife KilcoyneSusanna I Lee
Sep 19, 2020·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Basia M MichalskiM Laurin Council
Feb 26, 2021·Clinical Nuclear Medicine·Kgomotso M G MokoalaMike M Sathekge
May 8, 2021·Journal of the American College of Radiology : JACR·UNKNOWN Expert Panel on GYN and OB ImagingPhyllis Glanc
Sep 23, 2021·Insights Into Imaging·Olivera NikolićUNKNOWN ESUR Female Pelvic Imaging Working Group

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