PMID: 3766137Jun 1, 1986Paper

Carcinosarcoma of the gallbladder. Report of a case and review of the literature

Acta Pathologica Japonica
S InoshitaM Enjoji

Abstract

An extremely rare case of carcinosarcoma of the gallbladder is reported. The tumor presenting as a large, soft polypoid growth was microscopically characterized by an admixture of adenocarcinomatous and sarcomatous elements, the latter containing specific heterologous mesenchymal elements such as osteoid, cartilage, and rhabdomyoblasts. The cytoplasm of neoplastic rhabdomyoblasts offered unequivocal cross striations and was strongly positive for myoglobin, determined by the immunoperoxidase procedure. Metastatic tumors in the liver also exhibited a dual composition of adenocarcinoma and rhabdomyosarcoma. This appears to be the second documented case of this type of neoplasm with the rhabdomyosarcomatous component. The clinical settings and morbid prognosis were similar to events in cases of carcinoma of the gallbladder.

References

May 1, 1969·American Journal of Clinical Pathology·B H Smith, H B Taylor
Aug 1, 1973·Cancer·W R HiggsP H Jordan
Jun 1, 1971·The Journal of Pathology·T N MehrotraY P Naithani
May 1, 1980·American Journal of Clinical Pathology·K S Mansori, S Y Cho
Jan 1, 1982·Virchows Archiv. A, Pathological Anatomy and Histology·D AldoviniR Togni

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinosarcoma

Carcinosarcoma is a malignant neoplasm that contains elements of carcinoma and sarcoma so extensively intermixed as to indicate neoplasia of epithelial and mesenchymal tissue. Discover the latest research on carcinosarcoma here.