Cardiac arrhythmias and sudden cardiac death in women

Zeitschrift für Kardiologie
C RoggeM Zehender

Abstract

Gender specific cardiac arrhythmias have been recognized for more than 80 years. The impact of gonadal steroids on the autonomic system and on the cellular electrophysiology of the cardiac autonomic system are discussed as is a direct genetic disposition on a cellular, functional or metabolic level. We nevertheless have to be aware of age- and gender-specific differences of heart diseases, which have an impact on the incidence, form and severity of cardiac arrhythmias. Gender-specific electrophysiologic differences like a higher basic heart rate and a longer QT-interval, beginning after puberty, are the main changes in ECGs in women and have a strong relationship to constitutional and hormonal influences. Supraventricular arrhythmias, i. e. in women sinus and AV-nodal-reentry tachycardias, less frequently Wolff-Parkinson-White tachycardias, may show clearly cyclical differences. Atrial fibrillation is more frequent in women, is more symptomatic, and there are more problems in therapy. Ventricular arrhythmias, occurring equally in healthy persons, show a strong relationship to coronary artery disease in men, which is less significant in women (in women more arrhythmogenic co-factors). Women suffer from acquired and congenital lo...Continue Reading

Citations

Jun 25, 2008·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Vera Regitz-ZagrosekChristoph Nienaber
Feb 22, 2012·Medizinische Klinik, Intensivmedizin und Notfallmedizin·M Rosenberg, N Frey

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