Cardiac arrhythmias in the human fetus

Pediatric Cardiology
C S Kleinman, R A Nehgme

Abstract

Fetal cardiac arrhythmias have been recognized with increasing frequency during the past several years. Most fetal arrythmias are intermittent extrasystoles, often presenting as irregular pauses of rhythm. These are significant only when they occur with appropriate timing to initiate sustained tachycardia, mediated by anatomic bypass pathways. The most common important fetal arrhythmias are: 1) supraventricular tachycardias, and 2) severe bradyarrhythmias, associated with complete heart block. Symptomatic fetal tachycardias are usually supraventricular in origin, and may be associated with the developmet of hydrops fetalis. These patients may respond to antiarrhythmic drug therapy, administered via maternal ingestion or via direct fetal injection. Such therapy should be offered with careful fetal and maternal monitoring, and must be based on a logical, sequential analysis of the electrical mechanism underlying the arrhythmia, and an appreciation of the pharmacology and pharmacokinetics of the maternal, placental fetal system. Bradycardia from complete heart block may either be associated with complex congential heart malformations involving the atrioventricular junction of the heart, or may present in fetuses with normal cardia...Continue Reading

Citations

May 13, 2005·European Journal of Pediatrics·Denise P KolditzMartin J Schalij
Aug 30, 2011·World Journal of Pediatrics : WJP·Kai-Yu ZhouQi Zhu
Aug 20, 2009·Cardiology in the Young·Rajka Lulić JurjevićSamo Vesel
Sep 1, 2005·Journal of Zhejiang University. Science. B·Hui LiTao Shang
May 23, 2014·Cardiovascular Journal of Africa·Fatih Köksal BinnetoğluGürkan Altun
Nov 1, 2008·Expert Opinion on Medical Diagnostics·Lisa K Hornberger
Nov 27, 2010·Early Human Development·Nathan D HahurijFrank P H A Vandenbussche
Apr 3, 2010·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Zeljko MikovicGordana Dragovic Lukic
Feb 5, 2008·Best Practice & Research. Clinical Obstetrics & Gynaecology·Olus Api, Julene S Carvalho
Jul 24, 2007·Current Problems in Cardiology·Afshan B Hameed, Mark S Sklansky
Oct 10, 2015·Journal of the American College of Cardiology·Rakesh GopinathannairBrian Olshansky
Apr 22, 2009·Prenatal Diagnosis·Angela E LinKaren W Gripp
Jan 24, 2009·Prenatal Diagnosis·Boonchai UerpairojkitDhiraphongs Charoenvidhya
May 23, 2006·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J M Simpson
Nov 30, 2006·Acta Paediatrica·Elhadi AburawiMichael Blackburn
May 27, 2010·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·Y SaemundssonS Gudmundsson
Aug 3, 2011·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Michele MiragoliJulia Gorelik
Mar 28, 2006·Reproductive Toxicology·Martina Ceckova-NovotnaFrantisek Staud
Mar 15, 2006·Seminars in Fetal & Neonatal Medicine·Christopher Wren
Feb 3, 2015·Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc·Angela AgostinelliLaura Burattini
Jun 22, 2011·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Kaiyu ZhouNan Guo
May 3, 2018·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Sailesh Kumar, Jade Lodge
Dec 17, 2017·Journal of the American Heart Association·Tarek AlsaiedAllison A Divanovic
Jul 4, 2006·Journal of Midwifery & Women's Health·Susan S Salazar
Jul 13, 2005·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·María M RodríguezPeter L Ferrer
Jun 2, 2017·The Open Biomedical Engineering Journal·Angela AgostinelliLaura Burattini
Feb 26, 2011·Pediatric Cardiology·Elisabeth MlczochManfred Marx
Jun 15, 2007·Journal of Community Health Nursing·M HorodynskiRosalie Shemanski
Jan 15, 2008·Journal of Cardiovascular Medicine·Michele D'AltoRaffaele Calabrò
Sep 9, 2008·Ultrasound Quarterly·Sima Naderi, John P McGahan
Feb 27, 2020·Journal of Cardiovascular Electrophysiology·Edward T O'LearyDouglas Y Mah
Apr 30, 2020·Current Medical Research and Opinion·Theodora A ManolisAntonis S Manolis
Jun 28, 2013·Obstetrical & Gynecological Survey·David E Abel
May 28, 2015·Indian Journal of Pediatrics·Bassel Mohammad NijresLiliana Morales
Sep 1, 2015·Obstetrical & Gynecological Survey·Anna E DeNobleEleanor J Rhee
Sep 27, 2012·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Jon A DetterichMark S Sklansky
Dec 23, 2004·Pacing and Clinical Electrophysiology : PACE·Silvia ComaniGian Luca Romani
Oct 18, 2020·Journal of Gynecology Obstetrics and Human Reproduction·Guy VaksmannEmmanuelle Henriet
Jun 12, 2021·Heart Rhythm O2·Raphael BartinJulien Stirnemann
Jul 3, 2021·Journal of Clinical Medicine·Alina VedutaPaolo Cavoretto
Dec 22, 2004·Prenatal Diagnosis·Jean-Claude Fouron

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