Cardiac dysrhythmias in children with idiopathic dilated or hypertrophic cardiomyopathy

Pediatric Cardiology
G MüllerD Wolf

Abstract

To assess the incidence and prognostic significance of cardiac dysrhythmias in children with idiopathic dilated or hypertrophic cardiomyopathy, the clinical course of 59 patients was retrospectively reviewed over a period of 27 years. Dilated cardiomyopathy (DCM) was diagnosed in 28 patients and hypertrophic cardiomyopathy (HCM) in 31 patients. The mean age at the time of diagnosis was 2.8 +/- 0.7 years in DCM patients and 6.7 +/- 0.8 years in HCM patients. Mean follow-up time after diagnosis of cardiomyopathy was 4.1 +/- 1.0 years in DCM patients and 6.6 +/- 0.8 years in HCM patients. Clinically significant cardiac dysrhythmias were found in 17 of 59 patients (29%): 7 of 28 patients (25%) with DCM and 10 of 31 patients (32%) with HCM. The initial diagnosis of a cardiac dysrhythmia was made by standard electrocardiography in 12 of 17 patients (71%) and by 24-hour Holter monitoring in 5 of 17 patients (29%). Ventricular dysrhythmias were present in 5 of 7 patients with dilated cardiomyopathy and in 5 of 10 patients with hypertrophic cardiomyopathy. During the followup time, death occurred in 18 of 59 patients (31%): 8 of 59 patients (14%) died from congestive heart failure and 10 of 59 patients (17%) died suddenly. Among the sud...Continue Reading

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Citations

Jan 25, 2007·Cardiology in the Young·Vitor Manuel P AzevedoJose Geraldo C Amino
Mar 8, 2006·The Canadian Journal of Cardiology·Lindsay M Ryerson, R Michael Giuffre
Sep 1, 2007·Progress in Pediatric Cardiology·Jorge A AlvarezSteven E Lipshultz
Jul 16, 2009·Pacing and Clinical Electrophysiology : PACE·Robert M Hamilton, Eduardo R Azevedo
Apr 2, 2008·Congenital Heart Disease·Charles I Berul, Anne M Dubin
Dec 21, 2004·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·David RosenthalJeffrey Towbin
Apr 10, 2008·Archives of Cardiovascular Diseases·I DenjoyA Leenhardt
Dec 26, 2006·Expert Review of Cardiovascular Therapy·Anne M Dubin, Charles I Berul
May 4, 2011·Journal of Enzyme Inhibition and Medicinal Chemistry·Başak GökçeFeray Köçkar

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