Cardiac efficiency in patients with Cheyne-Stokes respiration as a result of heart insufficiency during long-term nasal respiratory treatment with adaptive servo ventilation (AutoSet CS)

Zeitschrift für Kardiologie
S SchädlichW Schütte

Abstract

Cheyne-Stokes respiration (CSR) is known to be an important negative predictor of outcome in patients with congestive heart failure. The goal of this study was to investigate whether the use of adaptive servo ventilation (AutoSet CS) would permit sufficient suppression of this pathological breathing pattern and improve cardiac function in longterm use over 1 year. Inclusion criteria for the study were congestive heart failure (left ventricular ejection fraction 20-50%), proven CSR with a central apnea-hypopnea index (AHI) > 15/h and stable clinical status with standard medical therapy. Patients with obstructive sleep apnea and COPD were excluded. Twenty consecutive patients (16 male) age 65.5 years (range 48-77) were followed with full blood counts, blood gas analysis, lung function tests and questionnaires for cardiopulmonary capacities (Minnesota, MRC Scale) and sleepiness (Epworth Sleepiness Scale). In addition, we performed 6-min walk distance (6MWD), echocardiography and polysomnography just before and after adjusting to adaptive servo ventilation and 3 and 12 months later. Mean usage of adaptive servo ventilation was sufficient (4.3 +/- 2.1 h/day at 12 months). No significant changes in blood gas analysis, blood counts an...Continue Reading

Citations

Jul 24, 2008·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Olaf OldenburgDieter Horstkotte
Sep 14, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Olaf OldenburgDieter Horstkotte
May 20, 2008·European Journal of Heart Failure·Olaf OldenburgDieter Horstkotte
Sep 16, 2010·Current Opinion in Pulmonary Medicine·Lee K Brown
Feb 22, 2012·Herzschrittmachertherapie & Elektrophysiologie·R Augostini
Apr 24, 2015·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Dominik LinzOlaf Oldenburg
Sep 4, 2020·Sleep & Breathing = Schlaf & Atmung·Leonie KolbMaximilian Malfertheiner

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