Cardiac morphologic findings in patients with acute myocardial infarction treated with recombinant tissue plasminogen activator

The American Journal of Cardiology
S D GertzE Braunwald

Abstract

The hearts of 52 patients (aged 61 +/- 11 years, 34 men) who participated in the Thrombolysis in Myocardial Infarction (TIMI) Study and died from 5 hours to 260 days (median 2.7 days) after onset of chest pain were studied. One heart became available at cardiac transplantation. Of the 52 patients, 38 received recombinant tissue plasminogen activator (rt-PA) not followed by percutaneous transluminal coronary angioplasty (PTCA) or coronary artery bypass grafting (CABG). Eight had PTCA, and 6 had CABG. The infarcts were hemorrhagic by gross inspection (with histologic confirmation) in 23 patients, nonhemorrhagic in 20, not visible grossly in 2 and, in 7, there was no myocardial necrosis by either gross or histologic examination.(ABSTRACT TRUNCATED AT 250 WORDS)

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References

Jan 1, 1985·Virchows Archiv. A, Pathological Anatomy and Histopathology·R E TracyG Kissling

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Citations

Jul 19, 2002·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Cheng-Wen ChiangLong-An Hsu
Feb 1, 1993·Journal of the American College of Cardiology·R A Kloner
May 1, 1996·Journal of the American College of Cardiology·R C BeckerW J Rogers
Mar 9, 1995·Journal of Interventional Cardiology·C P CannonE M Antman
Dec 4, 1992·Annals of the New York Academy of Sciences·E Falk
Sep 3, 1991·The American Journal of Cardiology·E Falk
Nov 19, 2014·Nature Reviews. Cardiology·Ryanne P BetgemNiels van Royen
Dec 1, 1990·The American Journal of Cardiology·S D Gertz, W C Roberts
Dec 1, 1990·Postgraduate Medicine·K G Ro, H V Anderson
Oct 17, 2020·Cardiovascular Research·Xuekun WuKai C Wollert

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