Cardiac output and cardiopulmonary responses to exercise in heart failure: application of a new bio-reactance device

Journal of Cardiac Failure
Jonathan N MyersDaniel Burkhoff

Abstract

Cardiopulmonary exercise testing (CPX) is widely used to evaluate heart failure (HF) patients, but lacks information about ventricular performance. There is a need for a noninvasive cardiac output (CO) measurement. Twenty-three HF patients and 13 normals underwent CPX and CO measurements with a new, noninvasive, bioreactance technology based on assessment of relative phase shifts (d phi/d t) of electric currents injected across the thorax, heart rate, and ventricular ejection time. CO and oxygen uptake (VO2) closely paralleled each another during exercise, and peak CO was strongly correlated with peak VO2 (r = 0.73, P < .001). The relationships between peak VO2 and peak cardiac index (CI) were similar for directly measured CI (r = 0.61) and noninvasive CI (r = 0.61). The CO-VO2 relationship was also similar between the current study and previous studies from the literature, as evidenced by a similar line of best fit and 95% confidence limits. Maximal CO was significantly related to indices of ventilatory efficiency, including the VE/VCO2 slope (r = -0.47, P < .01), and the oxygen uptake efficiency slope (r = 0.67, P < .01). Noninvasive measurement of CO during exercise using a novel bioreactance-based device has potentially imp...Continue Reading

References

Sep 1, 1991·Annals of Internal Medicine·J Myers, V F Froelicher
Aug 1, 1967·Circulation·S JuliusJ Conway
Jan 1, 1983·The American Journal of Cardiology·M B HigginbothamF R Cobb
Oct 9, 2004·Blood Pressure Monitoring·Stephen J LeslieMartin A Denvir
Aug 17, 2006·Journal of Cardiac Failure·Jonathan MyersPaul Heidenreich
Nov 23, 2006·Journal of the American College of Cardiology·James D Thomas, Zoran B Popović
Mar 27, 2007·American Journal of Physiology. Heart and Circulatory Physiology·Hanan KerenPierre Squara
Apr 27, 2007·Intensive Care Medicine·Pierre SquaraClaude Dubois

❮ Previous
Next ❯

Citations

Mar 26, 2010·European Journal of Applied Physiology·Adrian ElliottLesley Ansley
May 22, 2013·Journal of Clinical Monitoring and Computing·David KoberSebastian Haas
Feb 1, 2011·American Journal of Physiology. Heart and Circulatory Physiology·Tieh-Cheng FuJong-Shyan Wang
Jun 2, 2014·European Journal of Applied Physiology·Shu-Chun HuangJong-Shyan Wang
Oct 7, 2014·Revista española de anestesiología y reanimación·J Ripollés Melchor, A Espinosa
Dec 7, 2014·Best Practice & Research. Clinical Anaesthesiology·Djordje G JakovljevicGuy A MacGowan
Mar 15, 2008·Journal of Clinical Monitoring and Computing·Nirav Y RavalDaniel Burkhoff
Jan 12, 2012·Journal of Clinical Monitoring and Computing·Djordje G JakovljevicMichael I Trenell
Feb 7, 2013·Journal of Cardiac Failure·Jonathan MyersEuan A Ashley
Sep 30, 2009·Journal of Cardiac Failure·Mathew M MaurerDonna M Mancini
Sep 18, 2009·Hemodialysis International·Niloufar KossariPierre Squara
Mar 3, 2009·Heart Failure Clinics·Garrie J Haas, Carl V Leier
Apr 28, 2016·Wilderness & Environmental Medicine·George W RodwayColin K Grissom
Apr 24, 2018·High Altitude Medicine & Biology·Shu-Chun HuangJong-Shyan Wang
Aug 3, 2011·Medicine and Science in Sports and Exercise·Sophie Antoine-JonvilleMark J Dayer
Jul 19, 2014·Current Opinion in Cardiology·Ross ArenaShane A Phillips
Aug 5, 2020·Expert Review of Cardiovascular Therapy·Ross ArenaAntonio Abbate
Jan 11, 2017·Medicine and Science in Sports and Exercise·Brittany ButtsRebecca A Gary
Oct 17, 2020·Journal of Cardiothoracic and Vascular Anesthesia·Bashar A W PandhitaDjordje G Jakovljevic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Epigenetics Insights from Twin Studies

Find the latest research on epigenetics and twin studies here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Regulation of Vocal-Motor Plasticity

Dopaminergic projections to the basal ganglia and nucleus accumbens shape the learning and plasticity of motivated behaviors across species including the regulation of vocal-motor plasticity and performance in songbirds. Discover the latest research on the regulation of vocal-motor plasticity here.

Myocardial Stunning

Myocardial stunning is a mechanical dysfunction that persists after reperfusion of previously ischemic tissue in the absence of irreversible damage including myocardial necrosis. Here is the latest research.