PMID: 11317704Apr 25, 2001Paper

Cardiac output changes during hyperbaric hyperoxia

International Archives of Occupational and Environmental Health
B NeubauerE Bettinghausen

Abstract

Increased ambient pressure and oxygen partial pressure (pO2) influence cardiovascular regulation during diving and caisson work. We measured the cardiac output (Q) in subjects who practiced moderate work at a usual diving depth of 30 m. In 23 healthy male Navy divers who performed steady state bicycle exercises (100 W workload) in a hyperbaric chamber Q was measured by a CO2-rebreathing technique at normal pressure (100 kPa) and at raised ambient pressure (400 kPa), in a random order. During the rebreathing maneuver the subjects were exposed to pO2 values which theoretically may have reached a maximum value of 87 kPa (normobaric) and 388 kPa (hyperbaric). During the experiments the ambient temperature ranged between 22 and 25 degrees C. There was a significant decrease of the directly measured Q, heart rate (HR) and the calculated stroke volume at depth when compared with normoxic and normobaric exercise. The decrease of Q amounted to 64% of the normobaric value (8.9 l min-1 versus 13.9 l min-1). The mean HR decreased from 104.7 min-1 (100 kPa) to 94.0 min-1 (400 kPa). The calculated mean stroke volume decreased from 133 ml (100 kPa) to 96 ml (400 kPa). During hyperoxic hyperbaria the peripheral vascular tonus increases due to ...Continue Reading

Citations

Mar 12, 2009·European Journal of Applied Physiology·Florian ChouchouFrédéric Roche
Oct 8, 2009·Cellular and Molecular Life Sciences : CMLS·José A L CalbetCarsten Lundby
Jul 5, 2013·Journal of Applied Physiology·Ivan T DemchenkoBarry W Allen

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