Nov 1, 1975

Cardiac output response to altered acid-base status during diethyl ether anaesthesia

Canadian Anaesthetists' Society Journal
J O SodipoL E Morris


The effects of acid-base changes on cardiac output during diethyl ether anaesthesia were studied in 25 mongrel dogs prepared by surgically implanting a plastic encased non-ferrous core electromagnetic probe on the ascending aorta. The findings are: (1) Metabolic acidaemia produced only slight decrease in cardiac output but a more marked fall became evident with decreasing pH(2) Respiratory acidaemia led to a slight rise in cardiac output. (3) Respiratory alkalaemia decreased cardiac output. (4) Metabolic alkalaemia also produced a decline in cardiac output.

Mentioned in this Paper

Metabolic Process, Cellular
Ethyl Ethers
Mixed breed dog
Carbonic Acid Ions
Insufflation Anesthesia
Anesthesia Procedures
Anesthetic ether
Acidosis, Respiratory

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