Cardiac Purkinje fibers and arrhythmias; The GK Moe Award Lecture 2015

Heart Rhythm : the Official Journal of the Heart Rhythm Society
Penelope A BoydenRichard B Robinson

Abstract

Purkinje fibers/cells continue to be a focus of arrhythmologists. Here we review several new ideas that have emerged in the literature and fold them into important new points. These points include the following: some proteins in Purkinje cells are specific to Purkinjes; pacemaker function in Purkinje may be similar to that of the sinus node cell; sink-source concerns about tracts/sheets of Purkinje fibers; role of Ito in arrhythmias; and genetic lesions in Purkinjes and their high impact on cardiac rhythm. Although new ideas about the remodeled Purkinje cell are not the focus of this review, one can easily imagine how Purkinjes and their function may be altered in diseased hearts.

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Citations

Dec 5, 2016·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Wei LiYi-Gang Li
Jun 27, 2017·Heart Rhythm : the Official Journal of the Heart Rhythm Society·Mark J ShenPeng-Sheng Chen
Apr 11, 2018·International Journal for Numerical Methods in Biomedical Engineering·Fernando BarberRafael Sebastian
May 28, 2017·Journal of the American Heart Association·Thomas A ReherPeng-Sheng Chen
Jun 6, 2019·Methods and Protocols·Tania ZagliaMarco Mongillo
Feb 23, 2020·PloS One·Alan SugrueChristopher J McLeod
May 10, 2020·American Journal of Physiology. Heart and Circulatory Physiology·Janine EbnerXaver Koenig
Oct 30, 2018·Journal of the American Heart Association·Christopher LiviaChristopher J McLeod
Apr 3, 2019·Frontiers in Physiology·Eva SamalVasanth Vedantham
Jul 21, 2020·Arrhythmia & Electrophysiology Review·Megan BarberRoy John
May 16, 2018·JACC. Clinical Electrophysiology·Raphael K SungMelvin Scheinman
Sep 13, 2017·ACS Applied Materials & Interfaces·Brisa PeñaLuisa Mestroni

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