Cardiac resynchronization therapy in a young patient with Duchenne muscular dystrophy

International Medical Case Reports Journal
Tamami KonoJitsuo Higaki

Abstract

A 32-year-old man with Duchenne muscular dystrophy (DMD) was admitted to the hospital because of worsening dyspnea and general fatigue. He had received medication therapy for cardiomyopathy with heart failure and home mechanical ventilation for respiratory failure. An electrocardiogram on admission showed intermittent third-degree atrioventricular block. Echocardiography showed global mild left ventricular systolic dysfunction with dyssynchrony (ejection fraction: 45%). He underwent implantation of a cardiac resynchronization therapy-defibrillator. His B-type natriuretic peptide level was improved after cardiac resynchronization therapy-defibrillator implantation, and he remains asymptomatic. The incidence of cardiomyopathy increases with age. By adulthood, 100% of patients have cardiac involvement.

Citations

Aug 26, 2017·Circulation·Brian FeingoldUNKNOWN American Heart Association Pediatric Heart Failure Committee of the Council on Cardiovascular Disease in the Young; Council
Apr 10, 2020·Current Heart Failure Reports·Jeffrey A ShihBrenda L Wong

❮ Previous
Next ❯

Methods Mentioned

BETA
pharmacotherapy
biopsy

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.