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Cardiac sympathetic denervation preceding motor signs in Parkinson disease

Cleveland Clinic Journal of Medicine

Apr 25, 2009

D S GoldsteinGraeme Eisenhofer

Abstract

There is substantial interest in identifying biomarkers to detect early Parkinson disease (PD). Cardiac noradrenergic denervation and attenuated baroreflex-cardiovagal function occur in de novo PD, but whether these abnormalities can precede PD has been unknown. Here we report the case ...read more

Mentioned in this Paper

Pathogenic Aspects
Pathogenesis
Myocardium
Parkinson Disease
Heart Ventricle
Signs and Symptoms
Parkinson Disease, LATE-ONSET
Heart Diseases
Noradrenergic
Baroreflex
Paper Details
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  • Citations10
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Cardiac sympathetic denervation preceding motor signs in Parkinson disease

Cleveland Clinic Journal of Medicine

Apr 25, 2009

D S GoldsteinGraeme Eisenhofer

PMID: 19376983

DOI: 10.3949/ccjm.76.s2.10

Abstract

There is substantial interest in identifying biomarkers to detect early Parkinson disease (PD). Cardiac noradrenergic denervation and attenuated baroreflex-cardiovagal function occur in de novo PD, but whether these abnormalities can precede PD has been unknown. Here we report the case ...read more

Mentioned in this Paper

Pathogenic Aspects
Pathogenesis
Myocardium
Parkinson Disease
Heart Ventricle
Signs and Symptoms
Parkinson Disease, LATE-ONSET
Heart Diseases
Noradrenergic
Baroreflex

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Inosine: Parkinson's Disease

Parkinson’s disease (PD) is a progressive neurodegenerative disorder that affects movement. Drug Inosine is proposed to slow progression of this disease. Here is the latest research on Inosine in PD.

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Parkinson's Disease is a progressive neurodegenerative disorder characterized by loss of muscle control, including trembling of the limbs and impaired balance. Here is the latest research.

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Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society

Sympathetic noradrenergic before striatal dopaminergic denervation: relevance to Braak staging of synucleinopathy

Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research SocietyJuly 29, 2011
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Paper Details
References
  • References
  • Citations10
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations10
1
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