PMID: 7813134Sep 1, 1994Paper

Cardiac systolic time intervals and other parameters of myocardial contractility as indices of fetal acid-base status

Baillière's Clinical Obstetrics and Gynaecology
R M Lewinsky


Electronic fetal heart rate monitoring has become the standard method for the assessment of fetal status during labour. Unfortunately, the hoped-for benefit from implementation of this technique has not been realized. The non-specific nature of FHR changes has led to undesirable side-effects, especially an increase in inappropriate operative interventions. Thus, there is an obvious need for methods which will improve upon the accuracy of FHR monitoring. There is substantial evidence for a tight coupling of fetal acid-base balance and myocardial contractility. This relationship has been established in experimental animal studies where fetuses were gradually rendered hypoxic and acidaemic while myocardial contractility was assessed by dP/dtmax and end-systolic elastance (Ees). Furthermore, the correlation between pH and indices of contractility extends over the entire range of clinical importance rather than being a terminal event. Systolic time intervals have long been recognized as good indicators of myocardial contractility. Recent advances in technology, have made their measurement in the human fetus by non-invasive means feasible. Substantial evidence has been accumulated, from both animal and human studies, to indicate that...Continue Reading


Jun 1, 1979·IEEE Transactions on Bio-medical Engineering·I Rapoport, A J Cousin
Mar 1, 1978·British Journal of Obstetrics and Gynaecology·H P RobinsonD M Clark
Feb 10, 1977·The New England Journal of Medicine·A M Weissler
Dec 1, 1990·European Journal of Obstetrics, Gynecology, and Reproductive Biology·G C SmithC R Whitfield
Sep 1, 1991·American Journal of Obstetrics and Gynecology·K van der MoorenJ W Wladimiroff
Oct 1, 1991·American Journal of Obstetrics and Gynecology·G Rizzo, D Arduini
Mar 1, 1990·The New England Journal of Medicine·R Freeman
Jan 1, 1989·Journal of Perinatal Medicine·T HataM Kitao
Mar 1, 1987·Baillière's Clinical Obstetrics and Gynaecology·S P Raymond, C R Whitfield
Jan 1, 1986·Circulation·K L ReedL Shenker
Dec 1, 1986·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J E FlemingC R Whitfield
Sep 1, 1974·American Journal of Obstetrics and Gynecology·L W OrganI H Rowe
May 1, 1981·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J L EversC B Martin
May 1, 1981·European Journal of Obstetrics, Gynecology, and Reproductive Biology·J L EversC B Martin
Aug 1, 1984·American Journal of Obstetrics and Gynecology·X De MuylderF Urfer
Feb 1, 1982·British Journal of Obstetrics and Gynaecology·J R DoigC R Whitfield
Jan 1, 1981·Journal of Perinatal Medicine·J Morgenstern
Jul 1, 1991·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·G LingmanM Stangenberg

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