Cardiac Tamponade Unmasking Recurrent Ovarian Cancer.

Curēus
Andrii MaryniakYi-Chun Lee

Abstract

Pericardial disease is a common manifestation of malignancy. Gynecologic malignancies such as ovarian cancer rarely present with cardiac involvement. Cardiac tamponade may be the initial presentation of malignancy in as many as half of pericardial disease cases. We report the case of a 60-year-old female with known ovarian adenocarcinoma, who achieved initial success with tumor debulking and adjuvant chemotherapy but was lost to follow-up. She presented again three years later with new-onset dyspnea and described a syncopal episode. A chest radiograph showed an enlarged cardiac silhouette and bilateral pleural effusions. Transthoracic echocardiography revealed a large pericardial effusion with diastolic collapse of the right atrium and ventricle, consistent with tamponade physiology. Subxiphoid pericardiocentesis and pigtail drain were placed under fluoroscopy with resolution of symptoms and no recurrence. Neoplastic etiology was confirmed by immunocytochemistry on cell block positive for PAX-8. As an adjunct or alternative to cytologic evaluation, diffusion-weighted magnetic resonance imaging and calculation of the apparent diffusion coefficient can be used to differentiate between malignant and benign effusions. Malignant per...Continue Reading

References

Mar 15, 1990·Cancer·E C Klatt, D R Heitz
Jun 1, 1993·Japanese Circulation Journal·T SeoK Kobayashi
May 21, 2005·The American Journal of Cardiology·Massimo ImazioRita Trinchero
Aug 24, 2010·Progress in Cardiovascular Diseases·Bernhard MaischSabine Pankuweit
Jan 31, 2013·Cancer Cytopathology·Ema A Dragoescu, Lina Liu
Jul 8, 2015·The Journal of Emergency Medicine·Tamar PerriJacob Korach
Nov 10, 2015·European Heart Journal·Yehuda Adler, Philippe Charron
Sep 23, 2016·Romanian Journal of Internal Medicine = Revue Roumaine De Médecine Interne·Alexandra KalogerakiGeorge E Chalkiadakis
Oct 13, 2017·European Heart Journal. Case Reports·Mohamad Jihad MansourElie J Chammas
Jan 9, 2020·CA: a Cancer Journal for Clinicians·Rebecca L SiegelAhmedin Jemal

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