Cardiac time intervals and the association with 2D-speckle-tracking, tissue Doppler and conventional echocardiography: the Thousand&1 Study

The International Journal of Cardiovascular Imaging
Tor Biering-SørensenMagnus Thorsten Jensen

Abstract

Cardiac time intervals (CTI) are prognostic above and beyond conventional echocardiographic measures. The explanation may be that CTI contain information about both systolic and diastolic measures; this is, however, unknown. The relationship between the CTI and systolic and diastolic function assessed by conventional, tissue Doppler (TDI) and speckle-tracking echocardiography (STE) was investigated. CTI and echocardiographic measurements, including conventional, STE, and TDI echocardiography, were studied in 1088 type 1 diabetes patients without known heart disease randomly selected from the out-patient clinic at Steno Diabetes Center. The CTI were obtained by TDI M-mode through the mitral leaflet and included the isovolumic relaxation time (IVRT), isovolumic contraction time (IVCT), and the myocardial performance index (MPI = (IVRT + IVCT)/ejection time). Standardized beta-values were assessed. Both systolic and diastolic measures associated with CTI. Conventional measures: left ventricular ejection fraction (stand. beta): MPI -0.34, IVRT 0.24, and IVCT -0.21, all p < 0.001. For the TDI measures, the most significant association was found with e': MPI (stand. beta: -0.30, p < 0.001) and IVRT (-0.35, p < 0.001) but no associati...Continue Reading

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Mar 10, 2015·JACC. Cardiovascular Imaging·Magnus Thorsten JensenJan Skov Jensen

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Citations

Apr 17, 2016·European Heart Journal Cardiovascular Imaging·Tor Biering-SørensenNiels Risum
Sep 6, 2017·European Journal of Heart Failure·Tor Biering-SørensenScott D Solomon
Jun 25, 2021·Mechanisms of Ageing and Development·Shubham BangaSusan E Howlett

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