PMID: 8254855Dec 22, 1993Paper

Cardiac transplantation for infants with hypoplastic left-heart syndrome

JAMA : the Journal of the American Medical Association
M ChiavarelliL L Bailey

Abstract

To determine whether cardiac transplantation improves the natural history of infants with hypoplastic left-heart syndrome and to examine differences in outcome as a function of the pretransplant period. Retrospective cohort study. Historical, clinical, and laboratory data were collected during the pretransplant period, the in-hospital period, and for up to 6 years following transplantation. Data were analyzed using the product-limit estimate and the log rank test. A tertiary, acute care, university teaching hospital. All 111 infants with hypoplastic left-heart syndrome who entered and completed a protocol leading to transplantation from November 19, 1985, to December 31, 1991. Infants who died while waiting for transplantation were included. Orthotopic cardiac allotransplantation. Pretransplant waiting mortality and its influence on posttransplant survival, operative (in-hospital or within 30 postoperative days in discharged patients) and intermediate-term mortality (5 years), and reoperation rates for cardiac surgery. Transplantation procedures were performed in 84 infants (76%; 95% confidence interval [CI], 66% to 83%) ranging in age from 3 hours to 151 days. Twenty-seven infants registered for transplantation died while awai...Continue Reading

Citations

May 18, 2005·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·M R K ChrisantUNKNOWN Pediatric Heart Transplant Study Group
Nov 4, 1998·The Annals of Thoracic Surgery·C I TchervenkovM J Béland
Apr 1, 2008·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Yanto Sandy TjangReiner Körfer
Sep 29, 2009·The Journal of Heart and Lung Transplantation : the Official Publication of the International Society for Heart Transplantation·Anne I DipchandUNKNOWN Pediatric Heart Transplant Study Investigators
Sep 10, 1998·The Journal of Thoracic and Cardiovascular Surgery·M L JacobsL L Bailey
Nov 1, 1995·The Journal of Pediatrics·M A Lovell, N L McDaniel
Mar 1, 1996·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·J RychikW I Norwood
Mar 23, 2002·The American Journal of Cardiology·Howard P Gutgesell, Jennifer Gibson
Oct 12, 2000·Journal of the American College of Cardiology·P C JenkinsG T O'Connor
Oct 5, 2001·Journal of the American College of Cardiology·P C JenkinsA N Tosteson
Jan 16, 2002·The Annals of Thoracic Surgery·D C DrinkwaterP A Chang
Mar 25, 2000·The Journal of Thoracic and Cardiovascular Surgery·D L WilliamsJ M Quaegebeur

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