Cardiac troponin T release after prolonged strenuous exercise.

Sports Medicine
E C H J MichielsenMarja P van Dieijen-Visser

Abstract

Over the past 2 decades, there has been a large interest in cardiac troponin T (cTnT) elevations, which are often seen following endurance sport events. There have been many reports on this topic, although sometimes with different approaches. We reviewed the available literature on cTnT elevations after prolonged strenuous exercise and discovered profound differences in the percentage of subjects reported to have elevated cTnT concentrations. This could partly be attributed to differences in immunoassay characteristics, such as cross-reactivity with skeletal troponin T, and the use of different cut-off values used in the different studies. The elevations were transient, with levels decreasing to pre-event concentrations within 24-48 hours. This might be explained by the relatively short half-life of cTnT, or water imbalance during and after the event. The release mechanism of cTnT, as well as the long-term positive or negative effects, remains unclear. Future research should therefore be aimed at clarifying the release mechanism of cTnT. Furthermore, the benefits and the possible long-term negative aspects of prolonged exercise should be evaluated.

References

Dec 1, 1989·Journal of Molecular and Cellular Cardiology·H A KatusW Kübler
Sep 1, 1981·British Journal of Sports Medicine·R Grogan
Dec 1, 1981·British Journal of Sports Medicine·T E Kinsey
Jun 1, 1995·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·C S Farah, F C Reinach
Mar 27, 1995·Annals of the New York Academy of Sciences·A KollerB Puschendorf
Jul 1, 1994·Coronary Artery Disease·A Shaknovich
Oct 1, 1993·Sports Medicine·C K Morris, V F Froelicher
Jul 1, 1996·Archives of Biochemistry and Biophysics·P Venditti, S Di Meo
Aug 1, 1996·Journal of the American College of Cardiology·B J MaronW O Roberts
Aug 15, 1996·The American Journal of Cardiology·L LaslettR Lind
May 1, 1996·International Journal of Sports Medicine·A BonettiG Tredici
Jan 1, 1996·European Journal of Applied Physiology and Occupational Physiology·J PasteneJ R Lacour
Aug 1, 1997·The American Journal of Cardiology·L Laslett, E Eisenbud
Aug 18, 1999·Clinica Chimica Acta; International Journal of Clinical Chemistry·A H Wu, L Ford
Oct 20, 1999·Medicine and Science in Sports and Exercise·A LucíaJ L Chicharro
Nov 26, 1999·JAMA : the Journal of the American Medical Association·A KollerH Moser
Jun 22, 2000·Medicine and Science in Sports and Exercise·G P WhyteW J McKenna
May 31, 2001·Medicine and Science in Sports and Exercise·A KollerH Moser
Oct 26, 2001·The American Journal of Cardiology·A J SiegelK B Lewandrowski
Feb 12, 2002·The American Journal of Cardiology·Guenther NeumayrHelmut Hoertnagl
Dec 11, 2002·American Journal of Clinical Pathology·Alexander KratzElizabeth Lee-Lewandrowski
Mar 6, 2003·Medicine and Science in Sports and Exercise·Arnold Koller
May 31, 2003·Scottish Medical Journal·R E ShaveP Collinson
Oct 3, 2003·Medicine and Science in Sports and Exercise·Daniel KönigHans-Hermann Dickhuth
Jan 31, 2004·British Journal of Sports Medicine·R E ShaveP Collinson
Jul 6, 2004·Medicine and Science in Sports and Exercise·Robert ShavePaul Collinson
Jul 28, 2004·Clinical Chemistry·Fred S Apple, MaryAnn M Murakami
Sep 3, 2004·The American Journal of Cardiology·Axel UrhausenWilfried Kindermann
Sep 9, 2004·Medicine and Science in Sports and Exercise·Robert ShaveDavid Gaze

❮ Previous
Next ❯

Citations

Sep 7, 2011·Clinical Chemistry and Laboratory Medicine : CCLM·Michael ChristChristian Müller
Mar 13, 2014·Experimental and Molecular Pathology·Alexander S StrengMarja P van Dieijen-Visser
Mar 10, 2010·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Alma M A MingelsMarja P van Dieijen-Visser
Jan 19, 2010·Clinica Chimica Acta; International Journal of Clinical Chemistry·Giuseppe Lippi, Giuseppe Banfi
Aug 6, 2017·Postgraduate Medical Journal·Mark Abela, Luke Sammut
Oct 30, 2014·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Chan-Ho ParkYi-Sub Kwak

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.