Cardio-oncology: an overview on outpatient management and future developments

Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation
A J TeskeF W Asselbergs

Abstract

Recent advances in the early detection and treatment of cancer have led to increasing numbers of cancer survivors worldwide. Nonetheless, despite major improvements in the outcome of these patients, long-term side effects of radio- and chemotherapy affect both patient survival and quality of life, independent of the oncological prognosis. Chemotherapy-related cardiac dysfunction is one of the most notorious short-term side effects of anticancer treatment, occurring in ~10% of patients. Progression to overt heart failure carries a strikingly poor prognosis with a 2-year mortality rate of 60%. Early detection of left ventricular damage by periodic monitoring and prompt initiation of heart failure treatment is key in improving cardiovascular prognosis. To meet the growing demand for a specialised interdisciplinary approach for the prevention and management of cardiovascular complications induced by cancer treatment, a new discipline termed cardio-oncology has evolved. However, an uniform, multidisciplinary approach is currently lacking in the Netherlands. This overview provides an introduction and comprehensive summary of this emerging discipline and offers a practical strategy for the outpatient management of this specific patien...Continue Reading

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Citations

Jun 17, 2020·Vascular Medicine·Jorie VersmissenJavid Moslehi
Oct 3, 2018·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·J M Leerink, Y M Pinto
Aug 7, 2019·Clinical Medicine Insights. Cardiology·Irving E PerezRhea Sancassani
Apr 13, 2019·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·S P SharmaO C Manintveld
Feb 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Qiao ZhangYanjiang Qiao
Nov 18, 2020·Netherlands Heart Journal : Monthly Journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation·J A M KamphuisA J Teske
Oct 7, 2020·Annual Review of Pharmacology and Toxicology·Konrad Teodor SawickiAlessandra Ghigo
Jan 14, 2021·World Journal of Clinical Oncology·Andrada Larisa DeacAnca Dana Buzoianu
Apr 18, 2021·Open Heart·Esmée C de BaatHeynric B Grotenhuis
Nov 21, 2021·Clinical Journal of Oncology Nursing

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Methods Mentioned

BETA
imaging technique

Clinical Trials Mentioned

NCT02943590
NCT02674204
NCT02096588
NCT03186404
NCT03265574
NCT01968200
NCT02177175
NCT01724450
NCT02717507
NCT01347970

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