Cardiocerebral resuscitation: a broader perspective

Journal of the American College of Cardiology
Daniel P Davis

Abstract

Historically, cardiac arrest outcomes have been stagnant with few therapies demonstrating clinical benefit. Recent advances in our understanding of cardiac arrest physiology and therapy have led to improved outcomes and renewed interest in defining the "optimal" approach. Cardiocerebral resuscitation (CCR) represents a bundle of specific therapies designed to enhance perfusion during cardiopulmonary arrest by emphasizing chest compressions over ventilations and "priming" the heart with compressions before and after defibrillation attempts. Implemented in Arizona and Wisconsin in 2003, patients treated using CCR appear to have improved outcomes compared with those treated under the 2000 guidelines from the International Liaison Committee on Resuscitation (ILCOR). This was particularly true in the subgroup of patients with bystander-witnessed collapse, who may represent a group with adequate oxygen reserves at the time of arrest and decreased requirement for immediate positive-pressure ventilation. Many components of CCR have since been incorporated in the 2005 ILCOR guidelines. Beyond the specific treatment approaches that define CCR, this alternative approach may represent the future of resuscitation science in which each insti...Continue Reading

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Citations

May 20, 2009·Current Opinion in Critical Care·Gordon A Ewy
Apr 1, 2017·Experimental Biology and Medicine·Gary F ScottRobert T Mallet
Sep 15, 2010·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jonathan R StudnekTom Blackwell
May 17, 2011·Journal of the American Geriatrics Society·M Jane MohlerArthur B Sanders

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