Cardiolipin at the heart of stress response across kingdoms

Plant Signaling & Behavior
Rosine de PaepeAntoine Danon

Abstract

Cardiolipin is a key phospholipid most specifically found in the membrane of mitochondria in yeasts, plants, and animals. Cardiolipins are essential for the maintenance, the integrity, and the dynamics of mitochondria. In most eukaryotes mitochondria play a central role in the response and adaptation to stress conditions especially through their importance in the control of programmed cell death. To assess the impact of the absence of cardiolipin, knock-down of the expression of cardiolipin synthase, the last enzyme of cardiolipin synthesis pathway in eukaryotes has been performed in yeasts, animals, and plants. These studies showed that cardiolipin is not only important for mitochondrial ultrastructure and for the stability of respiratory complexes, but it is also a key player in the response to stress, the formation of reactive oxygen species, and the execution of programmed cell death.

References

Sep 18, 1990·Biochimica Et Biophysica Acta·K T Tamai, M L Greenberg
Feb 22, 1980·Biochimica Et Biophysica Acta·R Bligny, R Douce
Nov 25, 1997·Biochimica Et Biophysica Acta·M Schlame, K Y Hostetler
Dec 19, 2000·Biochemical and Biophysical Research Communications·P VrekenP G Barth
May 23, 2002·Biochimie·Christophe FleuryJean-Luc Vayssière
Oct 17, 2003·The Journal of Biological Chemistry·Kathy PfeifferHermann Schägger
Dec 10, 2003·Journal of the American College of Cardiology·Michael SchlameThomas J J Blanck
Apr 20, 2004·Toxicology Letters·Sten Orrenius
Aug 18, 2004·Journal of Experimental Botany·Anja Krieger-Liszkay
Sep 21, 2004·Annual Review of Plant Biology·Klaus Apel, Heribert Hirt
Apr 7, 2005·FEBS Letters·Marcin NowickiMargrit Frentzen
Jan 13, 2006·Nature Chemical Biology·Sten Orrenius, Boris Zhivotovsky
Jan 24, 2008·Biochemical and Biophysical Research Communications·Jianfei JiangValerian E Kagan
Feb 8, 2008·Journal of Experimental Botany·Theresa J ReapePaul F McCabe
Mar 28, 2008·Nature Reviews. Genetics·Jesse D Woodson, Joanne Chory
Jun 24, 2008·Nature Reviews. Molecular Cell Biology·Yong-Ling P OwTak W Mak
Sep 19, 2008·Molecular Biology of the Cell·Shuliang ChenMiriam L Greenberg
Mar 17, 2009·Free Radical Biology & Medicine·Valerian E KaganGrigory Borisenko
Apr 18, 2009·Biochimica Et Biophysica Acta·Eugenia Mileykovskaya, William Dowhan
Sep 16, 2009·The Journal of Cell Biology·Rachel M DeVayJodi Nunnari
May 5, 2011·Biophysical Journal·Devrim AcehanMichael Schlame
Apr 20, 2012·European Journal of Cell Biology·Christina E N Lord, Arunika H L A N Gunawardena
Aug 7, 2013·Annual Review of Phytopathology·Martin B Dickman, Robert Fluhr
Jan 21, 2014·The Plant Cell·Ronghui PanJianping Hu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis