PMID: 6984983Dec 1, 1982Paper

Cardioplegia versus intermittent ischaemic arrest in coronary bypass surgery

Thorax
J R PepperM V Braimbridge

Abstract

No definitive method of myocardial preservation has been established and conclusions based on experimental data may not be applicable to patients with coronary artery disease. Fifty patients undergoing coronary bypass grafting were randomly assigned to one of two groups for myocardial preservation. In group A cold cardioplegia with external cardiac cooling was used and in group B ischaemic arrest with mild systemic cooling to 32 degrees C. Myocardial preservation was assessed by analysis of enzymes specific to the heart, left ventricular biopsy, and electrocardiography. Equal protection of the myocardium was provided in both groups but the mean cross-clamp time in group A was significantly longer than in group B. This implies that cardioplegia confers greater protection than intermittent ischaemic arrest.

References

Oct 1, 1978·The American Journal of Cardiology·G N OlingerF E Tristani
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Oct 1, 1979·The Annals of Thoracic Surgery·C J HiltonM T McEnany
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Citations

May 23, 2002·The Annals of Thoracic Surgery·Lucia RacoRussell J W Millner
Jan 1, 1998·Transplantation Proceedings·D Novitzky
Jun 5, 2002·Cardiovascular Surgery : Official Journal of the International Society for Cardiovascular Surgery·L K K TeohD M Yellon
Oct 12, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·U SunderdiekE Gams
Oct 1, 1989·The Journal of Surgical Research·F H van der VeenR S Reneman
Feb 1, 1985·The Annals of Thoracic Surgery·J E CoddV L Willman
Apr 14, 2005·Psychological Reports·Brenda L MoralesAmauri B Bartoszeck
Mar 4, 2006·Psychological Reports·Amauri B BartoszeckAaron J Place
Aug 12, 2019·Journal of Cardiothoracic and Vascular Anesthesia·Priyadharshanan AriyaratnamMichael E Cowen

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